Safety of cold snare polypectomy for duodenal adenomas in familial adenomatous polyposis

A prospective exploratory study

Kenta Hamada, Yoji Takeuchi, Hideki Ishikawa, Yasumasa Ezoe, Masamichi Arao, Sho Suzuki, Taro Iwatsubo, Minoru Kato, Yusuke Tonai, Satoki Shichijo, Yasushi Yamasaki, Noriko Matsuura, Hiroko Nakahira, Takashi Kanesaka, Sachiko Yamamoto, Tomofumi Akasaka, Noboru Hanaoka, Koji Higashino, Noriya Uedo, Ryu Ishihara & 2 others Hiroyuki Okada, Hiroyasu Iishi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background Cold snare polypectomy (CSP) to remove multiple duodenal adenomas (MDAs) in patients with familial adenomatous polyposis (FAP) could be an effective and less invasive method than more extensive surgery. The aim of the present study was to determine the safety of this procedure. Methods This prospective exploratory study included 10 consecutive patients with FAP and MDAs who underwent CSP for as many as 50 duodenal adenomas. The primary outcome was the incidence of severe adverse events. Results 10 patients were enrolled and underwent 332 CSPs from June 2016 to January 2017.?The median procedure time was 33 minutes (range 25?-?53), and the median number of polyps removed during a single session was 35 (range 10?-?50). Most of the removed polyps were?≤?10?mm. None of the 10 patients experienced a severe adverse event. One patient developed arterial bleeding during the procedure, but it was easily managed using hemoclips. Conclusions CSP for MDAs in patients with FAP was safe. The long-term efficacy of this procedure should be investigated.

Original languageEnglish
Pages (from-to)511-517
Number of pages7
JournalEndoscopy
Volume50
Issue number5
DOIs
Publication statusPublished - May 1 2018

Fingerprint

Adenomatous Polyposis Coli
Adenoma
Prospective Studies
Safety
Polyps
Hemorrhage
Incidence

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Hamada, K., Takeuchi, Y., Ishikawa, H., Ezoe, Y., Arao, M., Suzuki, S., ... Iishi, H. (2018). Safety of cold snare polypectomy for duodenal adenomas in familial adenomatous polyposis: A prospective exploratory study. Endoscopy, 50(5), 511-517. https://doi.org/10.1055/s-0043-124765

Safety of cold snare polypectomy for duodenal adenomas in familial adenomatous polyposis : A prospective exploratory study. / Hamada, Kenta; Takeuchi, Yoji; Ishikawa, Hideki; Ezoe, Yasumasa; Arao, Masamichi; Suzuki, Sho; Iwatsubo, Taro; Kato, Minoru; Tonai, Yusuke; Shichijo, Satoki; Yamasaki, Yasushi; Matsuura, Noriko; Nakahira, Hiroko; Kanesaka, Takashi; Yamamoto, Sachiko; Akasaka, Tomofumi; Hanaoka, Noboru; Higashino, Koji; Uedo, Noriya; Ishihara, Ryu; Okada, Hiroyuki; Iishi, Hiroyasu.

In: Endoscopy, Vol. 50, No. 5, 01.05.2018, p. 511-517.

Research output: Contribution to journalArticle

Hamada, K, Takeuchi, Y, Ishikawa, H, Ezoe, Y, Arao, M, Suzuki, S, Iwatsubo, T, Kato, M, Tonai, Y, Shichijo, S, Yamasaki, Y, Matsuura, N, Nakahira, H, Kanesaka, T, Yamamoto, S, Akasaka, T, Hanaoka, N, Higashino, K, Uedo, N, Ishihara, R, Okada, H & Iishi, H 2018, 'Safety of cold snare polypectomy for duodenal adenomas in familial adenomatous polyposis: A prospective exploratory study', Endoscopy, vol. 50, no. 5, pp. 511-517. https://doi.org/10.1055/s-0043-124765
Hamada, Kenta ; Takeuchi, Yoji ; Ishikawa, Hideki ; Ezoe, Yasumasa ; Arao, Masamichi ; Suzuki, Sho ; Iwatsubo, Taro ; Kato, Minoru ; Tonai, Yusuke ; Shichijo, Satoki ; Yamasaki, Yasushi ; Matsuura, Noriko ; Nakahira, Hiroko ; Kanesaka, Takashi ; Yamamoto, Sachiko ; Akasaka, Tomofumi ; Hanaoka, Noboru ; Higashino, Koji ; Uedo, Noriya ; Ishihara, Ryu ; Okada, Hiroyuki ; Iishi, Hiroyasu. / Safety of cold snare polypectomy for duodenal adenomas in familial adenomatous polyposis : A prospective exploratory study. In: Endoscopy. 2018 ; Vol. 50, No. 5. pp. 511-517.
@article{8a158111f49d4d94ba80b74040ce2d63,
title = "Safety of cold snare polypectomy for duodenal adenomas in familial adenomatous polyposis: A prospective exploratory study",
abstract = "Background Cold snare polypectomy (CSP) to remove multiple duodenal adenomas (MDAs) in patients with familial adenomatous polyposis (FAP) could be an effective and less invasive method than more extensive surgery. The aim of the present study was to determine the safety of this procedure. Methods This prospective exploratory study included 10 consecutive patients with FAP and MDAs who underwent CSP for as many as 50 duodenal adenomas. The primary outcome was the incidence of severe adverse events. Results 10 patients were enrolled and underwent 332 CSPs from June 2016 to January 2017.?The median procedure time was 33 minutes (range 25?-?53), and the median number of polyps removed during a single session was 35 (range 10?-?50). Most of the removed polyps were?≤?10?mm. None of the 10 patients experienced a severe adverse event. One patient developed arterial bleeding during the procedure, but it was easily managed using hemoclips. Conclusions CSP for MDAs in patients with FAP was safe. The long-term efficacy of this procedure should be investigated.",
author = "Kenta Hamada and Yoji Takeuchi and Hideki Ishikawa and Yasumasa Ezoe and Masamichi Arao and Sho Suzuki and Taro Iwatsubo and Minoru Kato and Yusuke Tonai and Satoki Shichijo and Yasushi Yamasaki and Noriko Matsuura and Hiroko Nakahira and Takashi Kanesaka and Sachiko Yamamoto and Tomofumi Akasaka and Noboru Hanaoka and Koji Higashino and Noriya Uedo and Ryu Ishihara and Hiroyuki Okada and Hiroyasu Iishi",
year = "2018",
month = "5",
day = "1",
doi = "10.1055/s-0043-124765",
language = "English",
volume = "50",
pages = "511--517",
journal = "Endoscopy",
issn = "0013-726X",
publisher = "Georg Thieme Verlag",
number = "5",

}

TY - JOUR

T1 - Safety of cold snare polypectomy for duodenal adenomas in familial adenomatous polyposis

T2 - A prospective exploratory study

AU - Hamada, Kenta

AU - Takeuchi, Yoji

AU - Ishikawa, Hideki

AU - Ezoe, Yasumasa

AU - Arao, Masamichi

AU - Suzuki, Sho

AU - Iwatsubo, Taro

AU - Kato, Minoru

AU - Tonai, Yusuke

AU - Shichijo, Satoki

AU - Yamasaki, Yasushi

AU - Matsuura, Noriko

AU - Nakahira, Hiroko

AU - Kanesaka, Takashi

AU - Yamamoto, Sachiko

AU - Akasaka, Tomofumi

AU - Hanaoka, Noboru

AU - Higashino, Koji

AU - Uedo, Noriya

AU - Ishihara, Ryu

AU - Okada, Hiroyuki

AU - Iishi, Hiroyasu

PY - 2018/5/1

Y1 - 2018/5/1

N2 - Background Cold snare polypectomy (CSP) to remove multiple duodenal adenomas (MDAs) in patients with familial adenomatous polyposis (FAP) could be an effective and less invasive method than more extensive surgery. The aim of the present study was to determine the safety of this procedure. Methods This prospective exploratory study included 10 consecutive patients with FAP and MDAs who underwent CSP for as many as 50 duodenal adenomas. The primary outcome was the incidence of severe adverse events. Results 10 patients were enrolled and underwent 332 CSPs from June 2016 to January 2017.?The median procedure time was 33 minutes (range 25?-?53), and the median number of polyps removed during a single session was 35 (range 10?-?50). Most of the removed polyps were?≤?10?mm. None of the 10 patients experienced a severe adverse event. One patient developed arterial bleeding during the procedure, but it was easily managed using hemoclips. Conclusions CSP for MDAs in patients with FAP was safe. The long-term efficacy of this procedure should be investigated.

AB - Background Cold snare polypectomy (CSP) to remove multiple duodenal adenomas (MDAs) in patients with familial adenomatous polyposis (FAP) could be an effective and less invasive method than more extensive surgery. The aim of the present study was to determine the safety of this procedure. Methods This prospective exploratory study included 10 consecutive patients with FAP and MDAs who underwent CSP for as many as 50 duodenal adenomas. The primary outcome was the incidence of severe adverse events. Results 10 patients were enrolled and underwent 332 CSPs from June 2016 to January 2017.?The median procedure time was 33 minutes (range 25?-?53), and the median number of polyps removed during a single session was 35 (range 10?-?50). Most of the removed polyps were?≤?10?mm. None of the 10 patients experienced a severe adverse event. One patient developed arterial bleeding during the procedure, but it was easily managed using hemoclips. Conclusions CSP for MDAs in patients with FAP was safe. The long-term efficacy of this procedure should be investigated.

UR - http://www.scopus.com/inward/record.url?scp=85040798651&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85040798651&partnerID=8YFLogxK

U2 - 10.1055/s-0043-124765

DO - 10.1055/s-0043-124765

M3 - Article

VL - 50

SP - 511

EP - 517

JO - Endoscopy

JF - Endoscopy

SN - 0013-726X

IS - 5

ER -