S-[2-Carboxy-1-(1 H-imidazol-4-yl)ethyl]cysteine in normal human urine

M. Kinuta, N. Masuoka, K. Yao, J. Ohta, S. Yoshida, S. Futani, T. Ubuka

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


A compound, which had the same mobility on a high-voltage paper electrophoretogram and the same RF value on a thin-layer chromatogram as those of S-[2-carboxy-1-(1 H-imidazol-4-yl)ethyl]cysteine (I), was partially purified from human urine by ion-exchange column chromatography. The compound gave a signal at m/z 260 on its FAB mass spectrum, which was assigned as MH+ of compound I. These results suggest that the urinary compound is compound I and it is a physiological precursor of 3-[(carboxymethyl)thio]-3-(1 H-imidazol-4-yl)propanoic acid [Kinuta et al., (1991) Biochem J 275: 617-621].

Original languageEnglish
Pages (from-to)259-262
Number of pages4
JournalAmino Acids
Issue number2
Publication statusPublished - Jun 1 1991


  • Amino acids
  • Cysteine
  • Human urine
  • Imidazole compound
  • Paper electrophoresis

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Organic Chemistry


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