S-[2-Carboxy-1-(1 H-imidazol-4-yl)ethyl]cysteine in normal human urine

M. Kinuta, N. Masuoka, K. Yao, Jun Ohta, S. Yoshida, S. Futani, T. Ubuka

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A compound, which had the same mobility on a high-voltage paper electrophoretogram and the same RF value on a thin-layer chromatogram as those of S-[2-carboxy-1-(1 H-imidazol-4-yl)ethyl]cysteine (I), was partially purified from human urine by ion-exchange column chromatography. The compound gave a signal at m/z 260 on its FAB mass spectrum, which was assigned as MH+ of compound I. These results suggest that the urinary compound is compound I and it is a physiological precursor of 3-[(carboxymethyl)thio]-3-(1 H-imidazol-4-yl)propanoic acid [Kinuta et al., (1991) Biochem J 275: 617-621].

Original languageEnglish
Pages (from-to)259-262
Number of pages4
JournalAmino Acids
Volume1
Issue number2
DOIs
Publication statusPublished - Jun 1991

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Column chromatography
Ion Exchange Chromatography
Ion exchange
Urine
Electric potential
ethyl cysteine
propionic acid

Keywords

  • Amino acids
  • Cysteine
  • Human urine
  • Imidazole compound
  • Paper electrophoresis

ASJC Scopus subject areas

  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry

Cite this

Kinuta, M., Masuoka, N., Yao, K., Ohta, J., Yoshida, S., Futani, S., & Ubuka, T. (1991). S-[2-Carboxy-1-(1 H-imidazol-4-yl)ethyl]cysteine in normal human urine. Amino Acids, 1(2), 259-262. https://doi.org/10.1007/BF00806924

S-[2-Carboxy-1-(1 H-imidazol-4-yl)ethyl]cysteine in normal human urine. / Kinuta, M.; Masuoka, N.; Yao, K.; Ohta, Jun; Yoshida, S.; Futani, S.; Ubuka, T.

In: Amino Acids, Vol. 1, No. 2, 06.1991, p. 259-262.

Research output: Contribution to journalArticle

Kinuta, M, Masuoka, N, Yao, K, Ohta, J, Yoshida, S, Futani, S & Ubuka, T 1991, 'S-[2-Carboxy-1-(1 H-imidazol-4-yl)ethyl]cysteine in normal human urine', Amino Acids, vol. 1, no. 2, pp. 259-262. https://doi.org/10.1007/BF00806924
Kinuta M, Masuoka N, Yao K, Ohta J, Yoshida S, Futani S et al. S-[2-Carboxy-1-(1 H-imidazol-4-yl)ethyl]cysteine in normal human urine. Amino Acids. 1991 Jun;1(2):259-262. https://doi.org/10.1007/BF00806924
Kinuta, M. ; Masuoka, N. ; Yao, K. ; Ohta, Jun ; Yoshida, S. ; Futani, S. ; Ubuka, T. / S-[2-Carboxy-1-(1 H-imidazol-4-yl)ethyl]cysteine in normal human urine. In: Amino Acids. 1991 ; Vol. 1, No. 2. pp. 259-262.
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