S-100 beta positive human T lymphocytes: Their characteristics and behavior under normal and pathologic conditions

K. Takahashi, Tadashi Yoshino, K. Hayashi, H. Sonobe, Y. Ohtsuki

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The characteristics of human S-100 beta-positive T lymphocytes (S-100 beta+ T cells) and their fluctuation in peripheral blood under normal and various pathologic conditions were investigated. S-100 beta+ T cells were small lymphocytes with no particular subcellular structures and showed a proliferative response to mitogens. They were present mainly in peripheral blood under normal conditions but accumulated in T zones of lymph nodes with nonspecific T-zone hyperplasia, where numerous interdigitating reticulum cells existed. In healthy adults approximately 1% to 4% (mean 3.4%) of peripheral blood mononuclear cells were S-100 beta+ T cells. The proportion of S-100 beta+ T cells in peripheral blood tended to significantly decrease (

Original languageEnglish
Pages (from-to)214-220
Number of pages7
JournalBlood
Volume70
Issue number1
Publication statusPublished - 1987
Externally publishedYes

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T-cells
T-Lymphocytes
Blood
Reticulum
Lymphocytes
Mitogens
Dendritic Cells
Hyperplasia
Blood Cells
Lymph Nodes

ASJC Scopus subject areas

  • Hematology

Cite this

S-100 beta positive human T lymphocytes : Their characteristics and behavior under normal and pathologic conditions. / Takahashi, K.; Yoshino, Tadashi; Hayashi, K.; Sonobe, H.; Ohtsuki, Y.

In: Blood, Vol. 70, No. 1, 1987, p. 214-220.

Research output: Contribution to journalArticle

Takahashi, K, Yoshino, T, Hayashi, K, Sonobe, H & Ohtsuki, Y 1987, 'S-100 beta positive human T lymphocytes: Their characteristics and behavior under normal and pathologic conditions', Blood, vol. 70, no. 1, pp. 214-220.
Takahashi, K. ; Yoshino, Tadashi ; Hayashi, K. ; Sonobe, H. ; Ohtsuki, Y. / S-100 beta positive human T lymphocytes : Their characteristics and behavior under normal and pathologic conditions. In: Blood. 1987 ; Vol. 70, No. 1. pp. 214-220.
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