Chemical conversion of penicillin into cephalosporin has been a subject of intensive studies. The problems laid on elaborating synthesis of cephalosporin are as follows: (1) construction of cephem nuclea, (2) introduction of C(3) pendants, and (3) modification of C(7) amide pendants. We found that electrolytic ene-type chlorination of thiazolineazetidinones derived from penicillins is an efficient procedure to prove problem (2) and to solve problem (3).
|Number of pages||1|
|Journal||Electrochemical Society Extended Abstracts|
|Publication status||Published - Dec 1 1984|
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