Abstract
Since their discovery 15 years ago, the role of γδ T cells has remained somewhat elusive. Responses of γδ T cells have been found in numerous infectious and non-infectious diseases. New evidence points to γδ T cells' functioning in the airways to maintain normal airway responsiveness or tone. In the lung, distinct subsets of γδ T cell subsets seem to have specific roles, one subset promoting allergic inflammation, the other serving a protective role.
| Original language | English |
|---|---|
| Pages (from-to) | 151-158 |
| Number of pages | 8 |
| Journal | Respiratory Research |
| Volume | 1 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Nov 7 2000 |
| Externally published | Yes |
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Keywords
- Airway hyper-responsiveness
- Asthma
- Lymphocytes
- γδ T cells
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Medicine(all)
Cite this
Role of γδ T cells in protecting normal airway function. / Born, Willi K.; Lahn, Michael; Takeda, Katsuyuki; Kanehiro, Arihiko; O'Brien, Rebecca L.; Gelfand, Erwin W.
In: Respiratory Research, Vol. 1, No. 1, 07.11.2000, p. 151-158.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Role of γδ T cells in protecting normal airway function
AU - Born, Willi K.
AU - Lahn, Michael
AU - Takeda, Katsuyuki
AU - Kanehiro, Arihiko
AU - O'Brien, Rebecca L.
AU - Gelfand, Erwin W.
PY - 2000/11/7
Y1 - 2000/11/7
N2 - Since their discovery 15 years ago, the role of γδ T cells has remained somewhat elusive. Responses of γδ T cells have been found in numerous infectious and non-infectious diseases. New evidence points to γδ T cells' functioning in the airways to maintain normal airway responsiveness or tone. In the lung, distinct subsets of γδ T cell subsets seem to have specific roles, one subset promoting allergic inflammation, the other serving a protective role.
AB - Since their discovery 15 years ago, the role of γδ T cells has remained somewhat elusive. Responses of γδ T cells have been found in numerous infectious and non-infectious diseases. New evidence points to γδ T cells' functioning in the airways to maintain normal airway responsiveness or tone. In the lung, distinct subsets of γδ T cell subsets seem to have specific roles, one subset promoting allergic inflammation, the other serving a protective role.
KW - Airway hyper-responsiveness
KW - Asthma
KW - Lymphocytes
KW - γδ T cells
UR - http://www.scopus.com/inward/record.url?scp=0000531617&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0000531617&partnerID=8YFLogxK
U2 - 10.1186/rr26
DO - 10.1186/rr26
M3 - Article
C2 - 11667979
AN - SCOPUS:0000531617
VL - 1
SP - 151
EP - 158
JO - Respiratory Research
JF - Respiratory Research
SN - 1465-9921
IS - 1
ER -