Abstract
Background: The relationship between the properties of visual pigment and photoreceptor amplification efficiency is controversial. Results: Rhodopsin activates G protein more efficiently than cone pigments. Conclusion: Visual pigment properties are directly related to the photoreceptor sensitivity diversification. Significance: Amplification of cell responses is regulated by receptor molecules.
| Original language | English |
|---|---|
| Pages (from-to) | 5061-5073 |
| Number of pages | 13 |
| Journal | Journal of Biological Chemistry |
| Volume | 289 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Feb 21 2014 |
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Cell Biology
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Cite this
Kojima, K., Imamoto, Y., Maeda, R., Yamashita, T., & Shichida, Y. (2014). Rod visual pigment optimizes active state to achieve efficient g protein activation as compared with cone visual pigments. Journal of Biological Chemistry, 289(8), 5061-5073. https://doi.org/10.1074/jbc.M113.508507