TY - JOUR
T1 - Risk factors for low bone mineral density determined in patients in a general practice setting
AU - Ando, Akemi
AU - Mitsuhashi, Toshiharu
AU - Honda, Mitsugi
AU - Hanayama, Yoshihisa
AU - Hasegawa, Kou
AU - Obika, Mikako
AU - Kataoka, Hitomi
AU - Otsuka, Fumio
N1 - Funding Information:
We thank all of the physicians and medical staff who contributed to the patient care in the Department of General Medicine of Okayama University Hospital. We also thank Associate Professor Michio Yamamoto of the Graduate School of Environmental and Life Science, Okayama University for the advice on the statistical analyses.
Publisher Copyright:
© 2019 by Okayama University Medical School.
PY - 2019
Y1 - 2019
N2 - Osteoporosis increases the risk of bone fractures. It is diagnosed based on an individual's bone mineral density (BMD) or a fracture without trauma. BMD is usually measured by the dual energy X-ray absorptiometry (DXA) method. Here we investigated factors for the earliest possible prediction of decreased BMD by examining the relationships between patients' BMD values and changes in the patients' physical and laboratory values. We retrospectively reviewed the medical records of 149 patients who visited our department in 2014-2015 for a variety of reasons and underwent an area BMD examination by DXA. We analyzed the relationships between decreasing BMD and the patients' gender, age, body mass index (BMI), medical background, hemoglobin, electrolytes, and thyroid function. Thirty-nine of the patients were diagnosed with osteoporosis based on their T-scores. An adjusted analysis showed that female gender, aging, and increased serum calcium level were significantly related to decreasing femoral BMD, whereas high BMI was associated with an increase in femoral BMD. Collectively the results indicate that for the early detection of low BMD, it is important for general- practice physicians to consider conducting a BMD checkup when treating female and elderly patients with a low BMI and/or elevated serum calcium level.
AB - Osteoporosis increases the risk of bone fractures. It is diagnosed based on an individual's bone mineral density (BMD) or a fracture without trauma. BMD is usually measured by the dual energy X-ray absorptiometry (DXA) method. Here we investigated factors for the earliest possible prediction of decreased BMD by examining the relationships between patients' BMD values and changes in the patients' physical and laboratory values. We retrospectively reviewed the medical records of 149 patients who visited our department in 2014-2015 for a variety of reasons and underwent an area BMD examination by DXA. We analyzed the relationships between decreasing BMD and the patients' gender, age, body mass index (BMI), medical background, hemoglobin, electrolytes, and thyroid function. Thirty-nine of the patients were diagnosed with osteoporosis based on their T-scores. An adjusted analysis showed that female gender, aging, and increased serum calcium level were significantly related to decreasing femoral BMD, whereas high BMI was associated with an increase in femoral BMD. Collectively the results indicate that for the early detection of low BMD, it is important for general- practice physicians to consider conducting a BMD checkup when treating female and elderly patients with a low BMI and/or elevated serum calcium level.
KW - Body mass index (BMI)
KW - Bone mineral density (BMD)
KW - Female gender
KW - Hypercalcemia
KW - Osteoporosis
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M3 - Article
C2 - 31649366
AN - SCOPUS:85074064819
SN - 0386-300X
VL - 73
SP - 403
EP - 411
JO - Acta Medica Okayama
JF - Acta Medica Okayama
IS - 5
ER -