Risk factors for low bone mineral density determined in patients in a general practice setting

Research output: Contribution to journalArticle

Abstract

Osteoporosis increases the risk of bone fractures. It is diagnosed based on an individual's bone mineral density (BMD) or a fracture without trauma. BMD is usually measured by the dual energy X-ray absorptiometry (DXA) method. Here we investigated factors for the earliest possible prediction of decreased BMD by examining the relationships between patients' BMD values and changes in the patients' physical and laboratory values. We retrospectively reviewed the medical records of 149 patients who visited our department in 2014-2015 for a variety of reasons and underwent an area BMD examination by DXA. We analyzed the relationships between decreasing BMD and the patients' gender, age, body mass index (BMI), medical background, hemoglobin, electrolytes, and thyroid function. Thirty-nine of the patients were diagnosed with osteoporosis based on their T-scores. An adjusted analysis showed that female gender, aging, and increased serum calcium level were significantly related to decreasing femoral BMD, whereas high BMI was associated with an increase in femoral BMD. Collectively the results indicate that for the early detection of low BMD, it is important for general- practice physicians to consider conducting a BMD checkup when treating female and elderly patients with a low BMI and/or elevated serum calcium level.

Original languageEnglish
Pages (from-to)403-411
Number of pages9
JournalActa medica Okayama
Volume73
Issue number5
Publication statusPublished - Jan 1 2019

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General Practice
Bone Density
Minerals
Bone
Body Mass Index
Photon Absorptiometry
Thigh
Osteoporosis
Calcium
X rays
Bone Fractures
Serum
General Practitioners
Electrolytes
Medical Records
Thyroid Gland
Hemoglobins
Aging of materials
Wounds and Injuries

Keywords

  • Body mass index (BMI)
  • Bone mineral density (BMD)
  • Female gender
  • Hypercalcemia
  • Osteoporosis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

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title = "Risk factors for low bone mineral density determined in patients in a general practice setting",
abstract = "Osteoporosis increases the risk of bone fractures. It is diagnosed based on an individual's bone mineral density (BMD) or a fracture without trauma. BMD is usually measured by the dual energy X-ray absorptiometry (DXA) method. Here we investigated factors for the earliest possible prediction of decreased BMD by examining the relationships between patients' BMD values and changes in the patients' physical and laboratory values. We retrospectively reviewed the medical records of 149 patients who visited our department in 2014-2015 for a variety of reasons and underwent an area BMD examination by DXA. We analyzed the relationships between decreasing BMD and the patients' gender, age, body mass index (BMI), medical background, hemoglobin, electrolytes, and thyroid function. Thirty-nine of the patients were diagnosed with osteoporosis based on their T-scores. An adjusted analysis showed that female gender, aging, and increased serum calcium level were significantly related to decreasing femoral BMD, whereas high BMI was associated with an increase in femoral BMD. Collectively the results indicate that for the early detection of low BMD, it is important for general- practice physicians to consider conducting a BMD checkup when treating female and elderly patients with a low BMI and/or elevated serum calcium level.",
keywords = "Body mass index (BMI), Bone mineral density (BMD), Female gender, Hypercalcemia, Osteoporosis",
author = "Akemi Ando and Toshiharu Mitsuhashi and Mitsugi Honda and Yoshihisa Hanayama and Kou Hasegawa and Mikako Obika and Hitomi Kataoka and Fumio Otsuka",
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AU - Ando, Akemi

AU - Mitsuhashi, Toshiharu

AU - Honda, Mitsugi

AU - Hanayama, Yoshihisa

AU - Hasegawa, Kou

AU - Obika, Mikako

AU - Kataoka, Hitomi

AU - Otsuka, Fumio

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N2 - Osteoporosis increases the risk of bone fractures. It is diagnosed based on an individual's bone mineral density (BMD) or a fracture without trauma. BMD is usually measured by the dual energy X-ray absorptiometry (DXA) method. Here we investigated factors for the earliest possible prediction of decreased BMD by examining the relationships between patients' BMD values and changes in the patients' physical and laboratory values. We retrospectively reviewed the medical records of 149 patients who visited our department in 2014-2015 for a variety of reasons and underwent an area BMD examination by DXA. We analyzed the relationships between decreasing BMD and the patients' gender, age, body mass index (BMI), medical background, hemoglobin, electrolytes, and thyroid function. Thirty-nine of the patients were diagnosed with osteoporosis based on their T-scores. An adjusted analysis showed that female gender, aging, and increased serum calcium level were significantly related to decreasing femoral BMD, whereas high BMI was associated with an increase in femoral BMD. Collectively the results indicate that for the early detection of low BMD, it is important for general- practice physicians to consider conducting a BMD checkup when treating female and elderly patients with a low BMI and/or elevated serum calcium level.

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