Risk Factors for Low Birth Weight Infants in Japan

Akira Babazono, Toshihide Tsuda, Eiji Yamamoto, Yoshio Mino, Tsuneko Babazono, Yoshiki Kishi, Jun Sigemi, Takanori Ogawa, Hideyasu Aoyama

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Prevalence of low birth weight infants in Japan has been increasing, although infant mortality is the lowest in the world. We conducted a population based case-control study to clarify risk factors for low birth weight infants in Japan. Information was obtained by questionnaire. The response rate was 78.9% from 402 cases and 804 controls. The majority of low birth weight infants belongs to full-term case group. This is considered to be an important factor for low infant mortality in Japan. We examined potential risk factors by a multiple logistic regression model. Lower maternal academic career and toxemia were identified as significant risk factors for pre-term low birth weight infants, while maternal shorter height, lower prepregnancy weight, maternal smoking and employment during pregnancy and hypertension were identified as significant risk factors for full-term low birth weight infants. The Japanese small physique and prevalent hypertension are considered to be causes for the high prevalence of low birth weight infants. J Epidemiol, 1994 ; 4: 91-98.

Original languageEnglish
Pages (from-to)91-98
Number of pages8
JournalJournal of epidemiology
Issue number2
Publication statusPublished - 1994


  • case-control study
  • japan
  • logistic regression model
  • low birth weight infant

ASJC Scopus subject areas

  • Epidemiology


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