Risk factors for early and late postoperative complications of patients with endometrial cancer

Junichi Kodama, Noriko Seki, Yojiro Ojima, Keiichiro Nakamura, Atsushi Hongo, Yuji Hiramatsu

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Objective: We have routinely performed staging with pelvic and/or paraaortic lymphadenectomy in patients with endometrial cancer having moderate to high risk for lymph node metastasis. The aim of this study was to investigate the risk factors for the occurrence of early and late postoperative complications in patients managed primarily by surgery in our institution. Study design: Two-hundred and fifty-nine consecutive cases of endometrial cancer were enrolled in the study. Past history, body mass index, type of surgery, intraoperative findings, and follow-up information were collected from patient charts. Of these, 200, 127, and 30 patients underwent systematic pelvic lymphadenectomy, systematic paraaortic lymphadenectomy, and radical hysterectomy, respectively. The median numbers of dissected pelvic and paraaortic lymph nodes were 32 and 14, respectively. Results: None of the complications resulted in death. Of the study population, 36 early complications and 34 late complications occurred. Overall 65 patients (25.1%) had at least one complication. Multivariate analysis revealed that a longer operative time and paraaortic lymphadenectomy were independent predictors for the occurrence of early and late postoperative complications, respectively. Conclusions: Since the therapeutic value of lymphadenectomy is still under evaluation, the indications for systematic pelvic and paraaortic lymphadenectomy should be carefully considered.

Original languageEnglish
Pages (from-to)222-226
Number of pages5
JournalEuropean Journal of Obstetrics Gynecology and Reproductive Biology
Volume124
Issue number2
DOIs
Publication statusPublished - Feb 1 2006

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Endometrial Neoplasms
Lymph Node Excision
Lymph Nodes
Operative Time
Hysterectomy
Body Mass Index
Multivariate Analysis
Neoplasm Metastasis
Population

Keywords

  • Complication
  • Endometrial cancer
  • Lymphadenectomy
  • Surgery

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

Cite this

Risk factors for early and late postoperative complications of patients with endometrial cancer. / Kodama, Junichi; Seki, Noriko; Ojima, Yojiro; Nakamura, Keiichiro; Hongo, Atsushi; Hiramatsu, Yuji.

In: European Journal of Obstetrics Gynecology and Reproductive Biology, Vol. 124, No. 2, 01.02.2006, p. 222-226.

Research output: Contribution to journalArticle

Kodama, Junichi ; Seki, Noriko ; Ojima, Yojiro ; Nakamura, Keiichiro ; Hongo, Atsushi ; Hiramatsu, Yuji. / Risk factors for early and late postoperative complications of patients with endometrial cancer. In: European Journal of Obstetrics Gynecology and Reproductive Biology. 2006 ; Vol. 124, No. 2. pp. 222-226.
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AU - Hiramatsu, Yuji

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