Right ventricular stiffness constant as a predictor of postoperative hemodynamics in patients with hypoplastic right ventricle: A theoretical analysis

One and a half ventricle repair (1.5VR) is a surgical option for hypoplastic right ventricle (RV). The benefits of this procedure compared to biventricular repair (2VR) or Fontan operation remain unsettled. To compare postoperative hemodynamics, we performed a theoretical analysis using a computational model based on lumpedparameter state-variable equations. We varied the RV stiffness constant (B_RV) to simulate the various RV hypoplasia, and estimated hemodynamics for a given B_RV. With B _RV < 150% of normal, cardiac output was the largest in 2VR. With B_RV 150%, cardiac output became larger in 1.5VR than in 2VR. With B_RV> 250%, RV end-diastolic volume was almost the same between 1.5VR and 2VR, and a rapid increase in atrial pressure precluded the use of 1.5VR. These results indicate that the beneficial effect of 1.5VR depends on the RV stiffness constant. Determination of management strategy should not only be based on the morphologic parameters but also on the physiological properties of RV.