Methoxy-substituted 1,6-enynes react with arylboronic acids in the presence of a rhodium(I)complex to give arylated cyclization products. This occurs by a multi-step mechanism consisting of rhodium/boron transmetalation, intermolecular carborhodation, intramolecular carborhodation, β-hydride elimination, hydro-rhodation, and β-oxygen elimination. A shift of the position of a carbon-carbon double bond is observed, suggesting that the β-hydride elimination/hydrorhodation process is repeatedly taking place.
ASJC Scopus subject areas
- Organic Chemistry