TY - JOUR
T1 - Rho family GTPase-dependent immunity in plants and animals
AU - Kawano, Yoji
AU - Kaneko-Kawano, Takako
AU - Shimamoto, K.
N1 - Publisher Copyright:
© 2014 Kawano, Kaneko-Kawano and Shimamoto.
PY - 2014/10/14
Y1 - 2014/10/14
N2 - In plants, sophisticated forms of immune systems have developed to cope with a variety of pathogens. Accumulating evidence indicates that Rac (also known as Rop), a member of the Rho family of small GTPases, is a key regulator of immunity in plants and animals. Like other small GTPases, Rac/Rop GTPases function as a molecular switch downstream of immune receptors by cycling between GDP-bound inactive and GTP-bound active forms in cells. Rac/Rop GTPases trigger various immune responses, thereby resulting in enhanced disease resistance to pathogens. In this review, we highlight recent studies that have contributed to our current understanding of the Rac/Rop family GTPases and the upstream and downstream proteins involved in plant immunity. We also compare the features of effector-triggered immunity between plants and animals, and discuss the in vivo monitoring of Rac/Rop activation.
AB - In plants, sophisticated forms of immune systems have developed to cope with a variety of pathogens. Accumulating evidence indicates that Rac (also known as Rop), a member of the Rho family of small GTPases, is a key regulator of immunity in plants and animals. Like other small GTPases, Rac/Rop GTPases function as a molecular switch downstream of immune receptors by cycling between GDP-bound inactive and GTP-bound active forms in cells. Rac/Rop GTPases trigger various immune responses, thereby resulting in enhanced disease resistance to pathogens. In this review, we highlight recent studies that have contributed to our current understanding of the Rac/Rop family GTPases and the upstream and downstream proteins involved in plant immunity. We also compare the features of effector-triggered immunity between plants and animals, and discuss the in vivo monitoring of Rac/Rop activation.
KW - Effector-triggered immunity
KW - PAMPs-triggered immunity
KW - Plant immunity
KW - Rac/Rop
KW - small GTPase
UR - http://www.scopus.com/inward/record.url?scp=84908001662&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84908001662&partnerID=8YFLogxK
U2 - 10.3389/fpls.2014.00522
DO - 10.3389/fpls.2014.00522
M3 - Article
AN - SCOPUS:84908001662
VL - 5
JO - Frontiers in Plant Science
JF - Frontiers in Plant Science
SN - 1664-462X
IS - OCT
M1 - 522
ER -