Abstract
The RhCl3·3H2O/i-Pr2NEt-catalyzed [2+2+2] cyclotrimerization of alkynes has been achieved. The reaction can be widely used for various alkynes and provides tri- or hexa-substituted benzenes regioselectively in high yields. The [2+2+2] cycloaddition of diynes and alkynes is also developed, and it affords benzene derivatives in moderate to high yields.
Original language | English |
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Pages (from-to) | 5800-5807 |
Number of pages | 8 |
Journal | Tetrahedron |
Volume | 64 |
Issue number | 24 |
DOIs | |
Publication status | Published - Jun 9 2008 |
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Keywords
- Cyclotrimerization
- Hexa-substituted benzene
- Rh/amine catalyst
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
Cite this
RhCl3/amine-catalyzed [2+2+2] cyclization of alkynes. / Yoshida, Kenta; Morimoto, Ichiro; Mitsudo, Koichi; Tanaka, Hideo.
In: Tetrahedron, Vol. 64, No. 24, 09.06.2008, p. 5800-5807.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - RhCl3/amine-catalyzed [2+2+2] cyclization of alkynes
AU - Yoshida, Kenta
AU - Morimoto, Ichiro
AU - Mitsudo, Koichi
AU - Tanaka, Hideo
PY - 2008/6/9
Y1 - 2008/6/9
N2 - The RhCl3·3H2O/i-Pr2NEt-catalyzed [2+2+2] cyclotrimerization of alkynes has been achieved. The reaction can be widely used for various alkynes and provides tri- or hexa-substituted benzenes regioselectively in high yields. The [2+2+2] cycloaddition of diynes and alkynes is also developed, and it affords benzene derivatives in moderate to high yields.
AB - The RhCl3·3H2O/i-Pr2NEt-catalyzed [2+2+2] cyclotrimerization of alkynes has been achieved. The reaction can be widely used for various alkynes and provides tri- or hexa-substituted benzenes regioselectively in high yields. The [2+2+2] cycloaddition of diynes and alkynes is also developed, and it affords benzene derivatives in moderate to high yields.
KW - Cyclotrimerization
KW - Hexa-substituted benzene
KW - Rh/amine catalyst
UR - http://www.scopus.com/inward/record.url?scp=43149113199&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=43149113199&partnerID=8YFLogxK
U2 - 10.1016/j.tet.2008.03.079
DO - 10.1016/j.tet.2008.03.079
M3 - Article
AN - SCOPUS:43149113199
VL - 64
SP - 5800
EP - 5807
JO - Tetrahedron
JF - Tetrahedron
SN - 0040-4020
IS - 24
ER -