Revisiting silicate substituted hydroxyapatite by solid-state NMR

G. Gasquères, C. Bonhomme, J. Maquet, F. Babonneau, Satoshi Hayakawa, T. Kanaya, A. Osaka

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Silicon-substituted hydroxyapatite (Si-HAp) has shown promising properties such as high-bone remodeling around implants. So far, the techniques used for the structural characterization of the Si-HAp have given indirect evidence of the presence of silicon inside the structure (by X-ray and neutron diffraction). In this paper, we focus on Si-HAp derivatives obtained by a precipitation method (widely described in the literature). We demonstrate here by solid-state NMR spectroscopy that only a fraction of the silicon atoms are incorporated into the HAp lattice in the form of Q0 (SiO4 4-) species, for 4.6 wt% Si-HAp. A large amount of silicate units are located outside the HAp structure and correspond to silica-gel units. All results were established through 29Si MAS, 1H → 29Si CP MAS and T1ρ(1H) edited 1H → 29Si CP MAS experiments. This last pulse scheme acted as a powerful editing sequence, leading to unambiguous spectroscopic conclusions, concerning the location of the SiO4 4- moieties.

Original languageEnglish
Pages (from-to)342-346
Number of pages5
JournalMagnetic Resonance in Chemistry
Volume46
Issue number4
DOIs
Publication statusPublished - Apr 2008

Fingerprint

Silicates
Silicon
Durapatite
Hydroxyapatite
silicates
Nuclear magnetic resonance
solid state
nuclear magnetic resonance
silicon
Hydroxyapatites
Neutron Diffraction
editing
Bone Remodeling
Silica Gel
Silica gel
silica gel
Neutron diffraction
X-Ray Diffraction
bones
Nuclear magnetic resonance spectroscopy

Keywords

  • Si CP MAS experiments
  • Hydroxyapatite
  • Silicon-substituted HAp
  • Solid-state NMR
  • T ρ(H) edited H →

ASJC Scopus subject areas

  • Chemistry(all)
  • Physical and Theoretical Chemistry
  • Spectroscopy
  • Medicine(all)

Cite this

Gasquères, G., Bonhomme, C., Maquet, J., Babonneau, F., Hayakawa, S., Kanaya, T., & Osaka, A. (2008). Revisiting silicate substituted hydroxyapatite by solid-state NMR. Magnetic Resonance in Chemistry, 46(4), 342-346. https://doi.org/10.1002/mrc.2109

Revisiting silicate substituted hydroxyapatite by solid-state NMR. / Gasquères, G.; Bonhomme, C.; Maquet, J.; Babonneau, F.; Hayakawa, Satoshi; Kanaya, T.; Osaka, A.

In: Magnetic Resonance in Chemistry, Vol. 46, No. 4, 04.2008, p. 342-346.

Research output: Contribution to journalArticle

Gasquères, G, Bonhomme, C, Maquet, J, Babonneau, F, Hayakawa, S, Kanaya, T & Osaka, A 2008, 'Revisiting silicate substituted hydroxyapatite by solid-state NMR', Magnetic Resonance in Chemistry, vol. 46, no. 4, pp. 342-346. https://doi.org/10.1002/mrc.2109
Gasquères, G. ; Bonhomme, C. ; Maquet, J. ; Babonneau, F. ; Hayakawa, Satoshi ; Kanaya, T. ; Osaka, A. / Revisiting silicate substituted hydroxyapatite by solid-state NMR. In: Magnetic Resonance in Chemistry. 2008 ; Vol. 46, No. 4. pp. 342-346.
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