Abstract
Silicon-substituted hydroxyapatite (Si-HAp) has shown promising properties such as high-bone remodeling around implants. So far, the techniques used for the structural characterization of the Si-HAp have given indirect evidence of the presence of silicon inside the structure (by X-ray and neutron diffraction). In this paper, we focus on Si-HAp derivatives obtained by a precipitation method (widely described in the literature). We demonstrate here by solid-state NMR spectroscopy that only a fraction of the silicon atoms are incorporated into the HAp lattice in the form of Q0 (SiO4 4-) species, for 4.6 wt% Si-HAp. A large amount of silicate units are located outside the HAp structure and correspond to silica-gel units. All results were established through 29Si MAS, 1H → 29Si CP MAS and T1ρ(1H) edited 1H → 29Si CP MAS experiments. This last pulse scheme acted as a powerful editing sequence, leading to unambiguous spectroscopic conclusions, concerning the location of the SiO4 4- moieties.
| Original language | English |
|---|---|
| Pages (from-to) | 342-346 |
| Number of pages | 5 |
| Journal | Magnetic Resonance in Chemistry |
| Volume | 46 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 2008 |
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Keywords
- Si CP MAS experiments
- Hydroxyapatite
- Silicon-substituted HAp
- Solid-state NMR
- T ρ(H) edited H →
ASJC Scopus subject areas
- Chemistry(all)
- Physical and Theoretical Chemistry
- Spectroscopy
- Medicine(all)
Cite this
Revisiting silicate substituted hydroxyapatite by solid-state NMR. / Gasquères, G.; Bonhomme, C.; Maquet, J.; Babonneau, F.; Hayakawa, Satoshi; Kanaya, T.; Osaka, A.
In: Magnetic Resonance in Chemistry, Vol. 46, No. 4, 04.2008, p. 342-346.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Revisiting silicate substituted hydroxyapatite by solid-state NMR
AU - Gasquères, G.
AU - Bonhomme, C.
AU - Maquet, J.
AU - Babonneau, F.
AU - Hayakawa, Satoshi
AU - Kanaya, T.
AU - Osaka, A.
PY - 2008/4
Y1 - 2008/4
N2 - Silicon-substituted hydroxyapatite (Si-HAp) has shown promising properties such as high-bone remodeling around implants. So far, the techniques used for the structural characterization of the Si-HAp have given indirect evidence of the presence of silicon inside the structure (by X-ray and neutron diffraction). In this paper, we focus on Si-HAp derivatives obtained by a precipitation method (widely described in the literature). We demonstrate here by solid-state NMR spectroscopy that only a fraction of the silicon atoms are incorporated into the HAp lattice in the form of Q0 (SiO4 4-) species, for 4.6 wt% Si-HAp. A large amount of silicate units are located outside the HAp structure and correspond to silica-gel units. All results were established through 29Si MAS, 1H → 29Si CP MAS and T1ρ(1H) edited 1H → 29Si CP MAS experiments. This last pulse scheme acted as a powerful editing sequence, leading to unambiguous spectroscopic conclusions, concerning the location of the SiO4 4- moieties.
AB - Silicon-substituted hydroxyapatite (Si-HAp) has shown promising properties such as high-bone remodeling around implants. So far, the techniques used for the structural characterization of the Si-HAp have given indirect evidence of the presence of silicon inside the structure (by X-ray and neutron diffraction). In this paper, we focus on Si-HAp derivatives obtained by a precipitation method (widely described in the literature). We demonstrate here by solid-state NMR spectroscopy that only a fraction of the silicon atoms are incorporated into the HAp lattice in the form of Q0 (SiO4 4-) species, for 4.6 wt% Si-HAp. A large amount of silicate units are located outside the HAp structure and correspond to silica-gel units. All results were established through 29Si MAS, 1H → 29Si CP MAS and T1ρ(1H) edited 1H → 29Si CP MAS experiments. This last pulse scheme acted as a powerful editing sequence, leading to unambiguous spectroscopic conclusions, concerning the location of the SiO4 4- moieties.
KW - Si CP MAS experiments
KW - Hydroxyapatite
KW - Silicon-substituted HAp
KW - Solid-state NMR
KW - T ρ(H) edited H →
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UR - http://www.scopus.com/inward/citedby.url?scp=42049116159&partnerID=8YFLogxK
U2 - 10.1002/mrc.2109
DO - 10.1002/mrc.2109
M3 - Article
C2 - 18306175
AN - SCOPUS:42049116159
VL - 46
SP - 342
EP - 346
JO - Magnetic Resonance in Chemistry
JF - Magnetic Resonance in Chemistry
SN - 0749-1581
IS - 4
ER -