Revised criteria for the early diagnosis of diabetic nephropathy

Shigeki Inomata, Masakazu Haneda, Tatsumi Moriya, Shigehiro Katayama, Yasuhiko Iwamoto, Hideto Sakai, Yasuhiko Tomino, Seiichi Matsuo, Yasushi Asano, Hirofumi Makino

Research output: Contribution to journalShort surveypeer-review

5 Citations (Scopus)


The Diabetic Nephropathy Committee recommends the use of revised criteria for the early diagnosis of diabetic nephropathy in Japan. The new criteria are as follows: 1) Urinary albumin should be determined by immunoassay using a morning spot urine sample in diabetic patients without proteinuria or with dipstick-positive (+1) proteinuria. 2) A urinary albumin-to-creatinine ratio ranging from 30 to 299 mg/gCr in 2 or more of 3 specimens may be diagnosed as microalbuminuria. 3) Two alternatives, i.e. the urinary albumin excretion rate of 30-299 mg/24 hr in 24 hr urine collection and 20-199 μg/min in timed urine collection can be used to detect microalbuminuria. 4) Renal hypertrophy and elevated urinary type IV collagen may indicate the existence of diabetic renal disease. 5) Microalbuminuria originating in nondiabetic diseases should be excluded.

Original languageEnglish
Pages (from-to)757-759
Number of pages3
JournalJournal of the Japan Diabetes Society
Issue number10
Publication statusPublished - Dec 7 2005
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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