Resonance Raman Spectra of Manganese-Porphyrins on Ion-Exchange Resins Exhibiting Uricase-Like Catalytic Activity1

Junichi Odo, Masaki Mifune, Akimasa Iwado, Tatsuya Karasudani, Hirotaka Hashimoto, Noriko Motohashi, Yoshimasa Tanaka, Yutaka Saito

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Ion-exchange resins modified with some manganese(III)-porphyrins (Mn3+-Pr) show a uricase-like catalytic activity, which is applicable to the determination of uric acid. The resonance Raman spectra of Mn3+-Pr indicate that Mn3+-porphyrins on modified resins are reduced to Mn2+-porphyrins with oxidizing uric acid; Mn2+-porphyrins then return to Mn3+-porphyrins by oxidation with O2 in the reaction system. It was concluded on the basis of these results that the modified resins show an uricase-like activity by repeating this redox cycle of manganese-porphyrins on the modified resins. Mn3+-Pr exhibited no oxidative catalytic activity for 7-methylated derivatives of uric acid, indicating that the nitrogen atom at the 7-position of uric acid plays an important role in the activity of Mn3+-Pr.

Original languageEnglish
Pages (from-to)555-559
Number of pages5
JournalAnalytical Sciences
Volume7
Issue number4
DOIs
Publication statusPublished - 1991

Keywords

  • manganese-porphyrin
  • Modified resin
  • porphyrin-core vibration
  • resonance Raman spectrum
  • uric acid
  • uricase-like activity

ASJC Scopus subject areas

  • Analytical Chemistry

Fingerprint Dive into the research topics of 'Resonance Raman Spectra of Manganese-Porphyrins on Ion-Exchange Resins Exhibiting Uricase-Like Catalytic Activity<sup>1</sup>'. Together they form a unique fingerprint.

  • Cite this