Residential radon exposure and lung cancer risk in Misasa, Japan: A case-control study

Tomotaka Sobue, Valerie S. Lee, Weimin Ye, Hiroshi Tanooka, Masaki Mifune, Akihiko Suyama, Taeko Koga, Hiroshige Morishima, Sohei Kondo

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

In order to investigate an association between residential radon exposure and risk of lung cancer, a case-control study was conducted in Misasa Town, Tottori Prefecture, Japan. The case series consisted of 28 people who had died of lung cancer in the years 1976-96 and 36 controls chosen randomly from the residents in 1976, matched by sex and year of birth. Individual residential radon concentrations were measured for 1 year with alpha track detectors. The average radon concentration was 46 Bq/m3 for cases and 51 Bq/m3 for controls. Compared to the level of 24 or less Bq/m3, the adjusted odds ratios of lung cancer associated with radon levels of 25-49, 50-99 and 100 or more Bq/m3, were 1.13 (95% confidence interval: 0.29-4.40), 1.23 (0.16-9.39) and 0.25 (0.03-2.33). respectively. None of the estimates showed statistical significance, due to small sample size. When the subjects were limited to only include residents of more than 30 years, the estimates did not change substantially. This study did not find that the risk pattern of lung cancer, possibly associated with residential radon exposure, in Misasa Town differed from patterns observed in other countries.

Original languageEnglish
Pages (from-to)81-92
Number of pages12
JournalJournal of Radiation Research
Volume41
Issue number2
Publication statusPublished - Jun 2000

Fingerprint

radon
Radon
lung neoplasms
case-control studies
lungs
Case-Control Studies
Lung Neoplasms
Japan
cancer
towns
estimates
Sample Size
odds ratio
detectors
confidence interval
confidence
Odds Ratio
Parturition
Confidence Intervals
intervals

Keywords

  • Alpha track detector
  • Cancer incidence
  • Case-control study
  • Lung cancer
  • Residential radon

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Radiation
  • Radiological and Ultrasound Technology

Cite this

Sobue, T., Lee, V. S., Ye, W., Tanooka, H., Mifune, M., Suyama, A., ... Kondo, S. (2000). Residential radon exposure and lung cancer risk in Misasa, Japan: A case-control study. Journal of Radiation Research, 41(2), 81-92.

Residential radon exposure and lung cancer risk in Misasa, Japan : A case-control study. / Sobue, Tomotaka; Lee, Valerie S.; Ye, Weimin; Tanooka, Hiroshi; Mifune, Masaki; Suyama, Akihiko; Koga, Taeko; Morishima, Hiroshige; Kondo, Sohei.

In: Journal of Radiation Research, Vol. 41, No. 2, 06.2000, p. 81-92.

Research output: Contribution to journalArticle

Sobue, T, Lee, VS, Ye, W, Tanooka, H, Mifune, M, Suyama, A, Koga, T, Morishima, H & Kondo, S 2000, 'Residential radon exposure and lung cancer risk in Misasa, Japan: A case-control study', Journal of Radiation Research, vol. 41, no. 2, pp. 81-92.
Sobue, Tomotaka ; Lee, Valerie S. ; Ye, Weimin ; Tanooka, Hiroshi ; Mifune, Masaki ; Suyama, Akihiko ; Koga, Taeko ; Morishima, Hiroshige ; Kondo, Sohei. / Residential radon exposure and lung cancer risk in Misasa, Japan : A case-control study. In: Journal of Radiation Research. 2000 ; Vol. 41, No. 2. pp. 81-92.
@article{eb5772422715454d84e808db22b4c167,
title = "Residential radon exposure and lung cancer risk in Misasa, Japan: A case-control study",
abstract = "In order to investigate an association between residential radon exposure and risk of lung cancer, a case-control study was conducted in Misasa Town, Tottori Prefecture, Japan. The case series consisted of 28 people who had died of lung cancer in the years 1976-96 and 36 controls chosen randomly from the residents in 1976, matched by sex and year of birth. Individual residential radon concentrations were measured for 1 year with alpha track detectors. The average radon concentration was 46 Bq/m3 for cases and 51 Bq/m3 for controls. Compared to the level of 24 or less Bq/m3, the adjusted odds ratios of lung cancer associated with radon levels of 25-49, 50-99 and 100 or more Bq/m3, were 1.13 (95{\%} confidence interval: 0.29-4.40), 1.23 (0.16-9.39) and 0.25 (0.03-2.33). respectively. None of the estimates showed statistical significance, due to small sample size. When the subjects were limited to only include residents of more than 30 years, the estimates did not change substantially. This study did not find that the risk pattern of lung cancer, possibly associated with residential radon exposure, in Misasa Town differed from patterns observed in other countries.",
keywords = "Alpha track detector, Cancer incidence, Case-control study, Lung cancer, Residential radon",
author = "Tomotaka Sobue and Lee, {Valerie S.} and Weimin Ye and Hiroshi Tanooka and Masaki Mifune and Akihiko Suyama and Taeko Koga and Hiroshige Morishima and Sohei Kondo",
year = "2000",
month = "6",
language = "English",
volume = "41",
pages = "81--92",
journal = "Journal of Radiation Research",
issn = "0449-3060",
publisher = "Japan Radiation Research Society",
number = "2",

}

TY - JOUR

T1 - Residential radon exposure and lung cancer risk in Misasa, Japan

T2 - A case-control study

AU - Sobue, Tomotaka

AU - Lee, Valerie S.

AU - Ye, Weimin

AU - Tanooka, Hiroshi

AU - Mifune, Masaki

AU - Suyama, Akihiko

AU - Koga, Taeko

AU - Morishima, Hiroshige

AU - Kondo, Sohei

PY - 2000/6

Y1 - 2000/6

N2 - In order to investigate an association between residential radon exposure and risk of lung cancer, a case-control study was conducted in Misasa Town, Tottori Prefecture, Japan. The case series consisted of 28 people who had died of lung cancer in the years 1976-96 and 36 controls chosen randomly from the residents in 1976, matched by sex and year of birth. Individual residential radon concentrations were measured for 1 year with alpha track detectors. The average radon concentration was 46 Bq/m3 for cases and 51 Bq/m3 for controls. Compared to the level of 24 or less Bq/m3, the adjusted odds ratios of lung cancer associated with radon levels of 25-49, 50-99 and 100 or more Bq/m3, were 1.13 (95% confidence interval: 0.29-4.40), 1.23 (0.16-9.39) and 0.25 (0.03-2.33). respectively. None of the estimates showed statistical significance, due to small sample size. When the subjects were limited to only include residents of more than 30 years, the estimates did not change substantially. This study did not find that the risk pattern of lung cancer, possibly associated with residential radon exposure, in Misasa Town differed from patterns observed in other countries.

AB - In order to investigate an association between residential radon exposure and risk of lung cancer, a case-control study was conducted in Misasa Town, Tottori Prefecture, Japan. The case series consisted of 28 people who had died of lung cancer in the years 1976-96 and 36 controls chosen randomly from the residents in 1976, matched by sex and year of birth. Individual residential radon concentrations were measured for 1 year with alpha track detectors. The average radon concentration was 46 Bq/m3 for cases and 51 Bq/m3 for controls. Compared to the level of 24 or less Bq/m3, the adjusted odds ratios of lung cancer associated with radon levels of 25-49, 50-99 and 100 or more Bq/m3, were 1.13 (95% confidence interval: 0.29-4.40), 1.23 (0.16-9.39) and 0.25 (0.03-2.33). respectively. None of the estimates showed statistical significance, due to small sample size. When the subjects were limited to only include residents of more than 30 years, the estimates did not change substantially. This study did not find that the risk pattern of lung cancer, possibly associated with residential radon exposure, in Misasa Town differed from patterns observed in other countries.

KW - Alpha track detector

KW - Cancer incidence

KW - Case-control study

KW - Lung cancer

KW - Residential radon

UR - http://www.scopus.com/inward/record.url?scp=0034200539&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034200539&partnerID=8YFLogxK

M3 - Article

C2 - 11037576

AN - SCOPUS:0034200539

VL - 41

SP - 81

EP - 92

JO - Journal of Radiation Research

JF - Journal of Radiation Research

SN - 0449-3060

IS - 2

ER -