TY - JOUR
T1 - Renal pathology of ANCA-related vasculitis
T2 - Proposal for standardization of pathological diagnosis in Japan
AU - Joh, Kensuke
AU - Muso, Eri
AU - Shigematsu, Hidekazu
AU - Nose, Masato
AU - Nagata, Michio
AU - Arimura, Yoshihiro
AU - Yumura, Wako
AU - Wada, Takashi
AU - Nitta, Kousaku
AU - Makino, Hirofumi
AU - Taguma, Yoshio
AU - Kaneoka, Hidetoshi
AU - Suzuki, Yuhsuke
AU - Kobayashi, Masaki
AU - Koyama, Akio
AU - Usui, Joichi
AU - Hashimoto, Hiroshi
AU - Ozaki, Shoichi
AU - Tomino, Yasuhiko
AU - Yamagata, Kunihiro
N1 - Funding Information:
The authors are grateful for the tremendous support of Kazuo Suzuki (Chiba University Graduate School of Medicine, Inflammation Program, Department of Immunology), Satoko Kawashima (First Department of Internal Medicine, Kyorin University School of Medicine), Hiroaki Komori (Department of Pathogenomics, Ehime University Graduate School of Medicine), Mitsuyo Itabashi (Department of Medicine, Kidney Center, Tokyo Women’s Medical University), Noriaki Sada (Departments of Medicine and Clinical Science Okayama University Graduate School of Medicine), Tomoyoshi Kimura (Department of Nephrology, Sendai Shakaihoken Hospital), Kengo Furuichi (Division of Blood Purification, Kanazawa University Hospital, Department of Gastroenterology and Nephrology), Yukio Yuzawa (Department of Nephrology, Nagoya University Graduate School of Medicine), and Akira Horikoshi (Division of Nephrology, Department of Internal Medicine, Juntendo University School of Medicine) and Hiroyuki Kanno, Department of Pathology, Iwate Medical University). This study was supported by a grant from the Japan Health Science Foundation on “Research on Health Sciences focusing on Drug Innovation, International Collaborative Research (SH 44410)” (Chairperson Hiroshi Hashimoto), Renal Pathology Committee of JMAAV (Japanese study group for MPO-ANCA-related vasculitis), the joint committee of “Progressive Renal Diseases” (Chairperson: Yasuhiko Tomino) and “Intractable Vasculitis Syndromes” (Chairperson: Shoichi Ozaki) of the Ministry of Health, Labor and Welfare of Japan.
PY - 2008/8
Y1 - 2008/8
N2 - Background: In Japan, systematic evaluation of the histologic parameters of anti-neutrophil cytoplasmic autoantibodies (ANCA)-related vasculitis has been performed according to the Japanese classification by Shigematsu et al. However, this classification is quite different from that of the European Vasculitis Study Group (EUVAS) classification. Therefore, a histological common basis is needed to compare Japanese histological data with the international database. Method: Histological parameters concerning glomerular, tubulointerstitial, and vascular lesions of ANCA-related vasculitis, which are indispensable for clinical management, were elucidated and defined by reviewing, utilizing the merits of, and amending the two scoring systems. Results and conclusion: A new comprehensive and standardized scoring system, by which histological quantitative assessment can provide evidence for therapy planning, has been developed for renal biopsy of Japanese ANCA-related vasculitis.
AB - Background: In Japan, systematic evaluation of the histologic parameters of anti-neutrophil cytoplasmic autoantibodies (ANCA)-related vasculitis has been performed according to the Japanese classification by Shigematsu et al. However, this classification is quite different from that of the European Vasculitis Study Group (EUVAS) classification. Therefore, a histological common basis is needed to compare Japanese histological data with the international database. Method: Histological parameters concerning glomerular, tubulointerstitial, and vascular lesions of ANCA-related vasculitis, which are indispensable for clinical management, were elucidated and defined by reviewing, utilizing the merits of, and amending the two scoring systems. Results and conclusion: A new comprehensive and standardized scoring system, by which histological quantitative assessment can provide evidence for therapy planning, has been developed for renal biopsy of Japanese ANCA-related vasculitis.
KW - ANCA-related vasculitis
KW - Glomerulonephritis
KW - Histopathological evaluation
KW - Microscopic polyangiitis
KW - Renal biopsy
KW - Renal limited vasculitis
KW - Wegener's granulomatosis
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U2 - 10.1007/s10157-008-0052-7
DO - 10.1007/s10157-008-0052-7
M3 - Article
C2 - 18425690
AN - SCOPUS:47649101209
SN - 1342-1751
VL - 12
SP - 277
EP - 291
JO - Clinical and Experimental Nephrology
JF - Clinical and Experimental Nephrology
IS - 4
ER -