TY - JOUR
T1 - Relationship of particulate matter and ozone with 3-nitrotyrosine in the atmosphere
AU - Ito, Tatsuo
AU - Ogino, Keiki
AU - Nagaoka, Kenjiro
AU - Takemoto, Kei
PY - 2018/5
Y1 - 2018/5
N2 - The prevalence of allergic diseases has increased in the past few decades. Bio-aerosol proteins and their chemical modifications, such as 3-nitrotyrosine (3-NT), in the atmosphere have been attracting attention due to their promotive effects on allergies. 3-NT is generated from the amino acid, tyrosine, through a reaction with ozone (O3) and nitrogen dioxide (NO2). However, the underlying mechanisms have not yet been elucidated in detail. Therefore, we measured 3-NT and evaluated the relationships among 3-NT and various pollutants such as sulfur dioxide (SO2), NOx (NO + NO2), ozone (O3), PM7, total suspended particulate matter (TSP) containing proteins, humidity, and temperature. 3-NT positively correlated with O3, SO2, humidity, and temperature, and negatively correlated with NOx. A multiple regression analysis showed that 3-NT positively associated with O3, humidity, and PM7. O3 positively associated with 3-NT and PM7, and negatively associated with NOx and humidity. These results suggest that 3-NT is generated from PM proteins through a reaction with O3 under high humidity conditions, and that the measurement of 3-NT is important and useful for the research of O3. Environmental data suggest that 3-NT is generated from PM proteins by the reaction of O3 under high humidity.
AB - The prevalence of allergic diseases has increased in the past few decades. Bio-aerosol proteins and their chemical modifications, such as 3-nitrotyrosine (3-NT), in the atmosphere have been attracting attention due to their promotive effects on allergies. 3-NT is generated from the amino acid, tyrosine, through a reaction with ozone (O3) and nitrogen dioxide (NO2). However, the underlying mechanisms have not yet been elucidated in detail. Therefore, we measured 3-NT and evaluated the relationships among 3-NT and various pollutants such as sulfur dioxide (SO2), NOx (NO + NO2), ozone (O3), PM7, total suspended particulate matter (TSP) containing proteins, humidity, and temperature. 3-NT positively correlated with O3, SO2, humidity, and temperature, and negatively correlated with NOx. A multiple regression analysis showed that 3-NT positively associated with O3, humidity, and PM7. O3 positively associated with 3-NT and PM7, and negatively associated with NOx and humidity. These results suggest that 3-NT is generated from PM proteins through a reaction with O3 under high humidity conditions, and that the measurement of 3-NT is important and useful for the research of O3. Environmental data suggest that 3-NT is generated from PM proteins by the reaction of O3 under high humidity.
KW - 3-Nitrotyrosine
KW - NOx
KW - Ozone
KW - Particulate matter
UR - http://www.scopus.com/inward/record.url?scp=85033377269&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85033377269&partnerID=8YFLogxK
U2 - 10.1016/j.envpol.2017.10.069
DO - 10.1016/j.envpol.2017.10.069
M3 - Article
C2 - 29129430
AN - SCOPUS:85033377269
VL - 236
SP - 948
EP - 952
JO - Environmental Pollution
JF - Environmental Pollution
SN - 0269-7491
ER -