Relationship between susceptibility to hemolytic-uremic syndrome and levels of globotriaosylceramide in human sera

S. Watarai; K. Yokota; Tana; T. Kishimoto; T. Kanadani; K. Taketa; K. Oguma

doi:10.1128/JCM.39.2.798-800.2001

Relationship between susceptibility to hemolytic-uremic syndrome and levels of globotriaosylceramide in human sera

S. Watarai, K. Yokota, Tana, T. Kishimoto, T. Kanadani, K. Taketa, K. Oguma

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

The relationship between differential susceptibility to hemolytic-uremic syndrome (HUS) and levels of globotriaosylceramide (Gb3) in serum was studied in patients infected with verotoxin-producing Escherichia coli (VTEC). The serum Gb3 levels in patients with HUS were lower than these in diarrheal patients without subsequent HUS or in patients without clinical symptoms, indicating that individuals with a lower content of serum Gb3 show a higher incidence of HUS following VTEC infection.

Original language	English
Pages (from-to)	798-800
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	39
Issue number	2
DOIs	https://doi.org/10.1128/JCM.39.2.798-800.2001
Publication status	Published - 2001

ASJC Scopus subject areas

Microbiology (medical)

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10.1128/JCM.39.2.798-800.2001

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abstract = "The relationship between differential susceptibility to hemolytic-uremic syndrome (HUS) and levels of globotriaosylceramide (Gb3) in serum was studied in patients infected with verotoxin-producing Escherichia coli (VTEC). The serum Gb3 levels in patients with HUS were lower than these in diarrheal patients without subsequent HUS or in patients without clinical symptoms, indicating that individuals with a lower content of serum Gb3 show a higher incidence of HUS following VTEC infection.",

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AU - Watarai, S.

AU - Yokota, K.

AU - Tana,

AU - Kishimoto, T.

AU - Kanadani, T.

AU - Taketa, K.

AU - Oguma, K.

PY - 2001

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AB - The relationship between differential susceptibility to hemolytic-uremic syndrome (HUS) and levels of globotriaosylceramide (Gb3) in serum was studied in patients infected with verotoxin-producing Escherichia coli (VTEC). The serum Gb3 levels in patients with HUS were lower than these in diarrheal patients without subsequent HUS or in patients without clinical symptoms, indicating that individuals with a lower content of serum Gb3 show a higher incidence of HUS following VTEC infection.

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Relationship between susceptibility to hemolytic-uremic syndrome and levels of globotriaosylceramide in human sera

Abstract

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