Relationship between susceptibility to hemolytic-uremic syndrome and levels of globotriaosylceramide in human sera

S. Watarai, K. Yokota, Tana, T. Kishimoto, T. Kanadani, K. Taketa, K. Oguma

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

The relationship between differential susceptibility to hemolytic-uremic syndrome (HUS) and levels of globotriaosylceramide (Gb3) in serum was studied in patients infected with verotoxin-producing Escherichia coli (VTEC). The serum Gb3 levels in patients with HUS were lower than these in diarrheal patients without subsequent HUS or in patients without clinical symptoms, indicating that individuals with a lower content of serum Gb3 show a higher incidence of HUS following VTEC infection.

Original languageEnglish
Pages (from-to)798-800
Number of pages3
JournalJournal of Clinical Microbiology
Volume39
Issue number2
DOIs
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Microbiology (medical)

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