Relationship between plasma progesterone concentration and number of conceptuses and their growth in superovulated cattle

Shuichi Matsuyama, Yosuke Sakaguchi, Koji Kimura

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Elevated concentrations of circulating progesterone (P4) in the immediate post-ovulation period are associated with advancement of conceptus elongation in cattle. Superovulated (SOV) cattle have not only elevated plasma P4 concentrations but also multiple embryos in the uterus because of the formation of multiple corpora lutea. We examined the relationship between plasma P4 concentration and uterine glucose level in the immediate post-ovulation period and the presence and growth of multiple conceptuses in SOV cattle. SOV cattle were artificially inseminated with frozen-thawed semen at standing estrus (day 0), and the conceptuses were recovered by nonsurgical flushing of the uterus on day 13. In the SOV cattle, there were quadratic relationships between plasma P4 concentration on days 4, 5 and 7 and conceptus length and between number of conceptuses in the uterus and conceptus length. These results suggest that conceptus growth in SOV cattle is regulated by both systemic P4 level and number of conceptuses and that there are ranges of plasma P4 concentrations and numbers of conceptuses in the uterus that are suitable for conceptus growth and development. Plasma P4 concentrations on days 5 and 7, but not the numbers of conceptuses, were quadratically correlated with uterine glucose levels on day 13 in SOV cattle. In addition, conceptus length was positively correlated with uterine glucose level in SOV cattle. Accordingly, regardless of the number of conceptuses in the uterus, the plasma P4 concentration was well correlated with the regulation of conceptus growth via changes in uterine glucose levels in SOV cattle.

Original languageEnglish
Pages (from-to)609-614
Number of pages6
JournalJournal of Reproduction and Development
Volume58
Issue number5
DOIs
Publication statusPublished - 2012
Externally publishedYes

Fingerprint

conceptus
progesterone
cattle
uterus
glucose
ovulation
corpus luteum
estrus
semen

Keywords

  • Cattle
  • Conceptus growth
  • Glucose
  • Progesterone
  • Superovulation

ASJC Scopus subject areas

  • Animal Science and Zoology

Cite this

Relationship between plasma progesterone concentration and number of conceptuses and their growth in superovulated cattle. / Matsuyama, Shuichi; Sakaguchi, Yosuke; Kimura, Koji.

In: Journal of Reproduction and Development, Vol. 58, No. 5, 2012, p. 609-614.

Research output: Contribution to journalArticle

@article{46e8355748714dd1a7671c2304a78bc3,
title = "Relationship between plasma progesterone concentration and number of conceptuses and their growth in superovulated cattle",
abstract = "Elevated concentrations of circulating progesterone (P4) in the immediate post-ovulation period are associated with advancement of conceptus elongation in cattle. Superovulated (SOV) cattle have not only elevated plasma P4 concentrations but also multiple embryos in the uterus because of the formation of multiple corpora lutea. We examined the relationship between plasma P4 concentration and uterine glucose level in the immediate post-ovulation period and the presence and growth of multiple conceptuses in SOV cattle. SOV cattle were artificially inseminated with frozen-thawed semen at standing estrus (day 0), and the conceptuses were recovered by nonsurgical flushing of the uterus on day 13. In the SOV cattle, there were quadratic relationships between plasma P4 concentration on days 4, 5 and 7 and conceptus length and between number of conceptuses in the uterus and conceptus length. These results suggest that conceptus growth in SOV cattle is regulated by both systemic P4 level and number of conceptuses and that there are ranges of plasma P4 concentrations and numbers of conceptuses in the uterus that are suitable for conceptus growth and development. Plasma P4 concentrations on days 5 and 7, but not the numbers of conceptuses, were quadratically correlated with uterine glucose levels on day 13 in SOV cattle. In addition, conceptus length was positively correlated with uterine glucose level in SOV cattle. Accordingly, regardless of the number of conceptuses in the uterus, the plasma P4 concentration was well correlated with the regulation of conceptus growth via changes in uterine glucose levels in SOV cattle.",
keywords = "Cattle, Conceptus growth, Glucose, Progesterone, Superovulation",
author = "Shuichi Matsuyama and Yosuke Sakaguchi and Koji Kimura",
year = "2012",
doi = "10.1262/jrd.2012-079",
language = "English",
volume = "58",
pages = "609--614",
journal = "Journal of Reproduction and Development",
issn = "0916-8818",
publisher = "Japanese Society of Animal Reproduction (JSAR)",
number = "5",

}

TY - JOUR

T1 - Relationship between plasma progesterone concentration and number of conceptuses and their growth in superovulated cattle

AU - Matsuyama, Shuichi

AU - Sakaguchi, Yosuke

AU - Kimura, Koji

PY - 2012

Y1 - 2012

N2 - Elevated concentrations of circulating progesterone (P4) in the immediate post-ovulation period are associated with advancement of conceptus elongation in cattle. Superovulated (SOV) cattle have not only elevated plasma P4 concentrations but also multiple embryos in the uterus because of the formation of multiple corpora lutea. We examined the relationship between plasma P4 concentration and uterine glucose level in the immediate post-ovulation period and the presence and growth of multiple conceptuses in SOV cattle. SOV cattle were artificially inseminated with frozen-thawed semen at standing estrus (day 0), and the conceptuses were recovered by nonsurgical flushing of the uterus on day 13. In the SOV cattle, there were quadratic relationships between plasma P4 concentration on days 4, 5 and 7 and conceptus length and between number of conceptuses in the uterus and conceptus length. These results suggest that conceptus growth in SOV cattle is regulated by both systemic P4 level and number of conceptuses and that there are ranges of plasma P4 concentrations and numbers of conceptuses in the uterus that are suitable for conceptus growth and development. Plasma P4 concentrations on days 5 and 7, but not the numbers of conceptuses, were quadratically correlated with uterine glucose levels on day 13 in SOV cattle. In addition, conceptus length was positively correlated with uterine glucose level in SOV cattle. Accordingly, regardless of the number of conceptuses in the uterus, the plasma P4 concentration was well correlated with the regulation of conceptus growth via changes in uterine glucose levels in SOV cattle.

AB - Elevated concentrations of circulating progesterone (P4) in the immediate post-ovulation period are associated with advancement of conceptus elongation in cattle. Superovulated (SOV) cattle have not only elevated plasma P4 concentrations but also multiple embryos in the uterus because of the formation of multiple corpora lutea. We examined the relationship between plasma P4 concentration and uterine glucose level in the immediate post-ovulation period and the presence and growth of multiple conceptuses in SOV cattle. SOV cattle were artificially inseminated with frozen-thawed semen at standing estrus (day 0), and the conceptuses were recovered by nonsurgical flushing of the uterus on day 13. In the SOV cattle, there were quadratic relationships between plasma P4 concentration on days 4, 5 and 7 and conceptus length and between number of conceptuses in the uterus and conceptus length. These results suggest that conceptus growth in SOV cattle is regulated by both systemic P4 level and number of conceptuses and that there are ranges of plasma P4 concentrations and numbers of conceptuses in the uterus that are suitable for conceptus growth and development. Plasma P4 concentrations on days 5 and 7, but not the numbers of conceptuses, were quadratically correlated with uterine glucose levels on day 13 in SOV cattle. In addition, conceptus length was positively correlated with uterine glucose level in SOV cattle. Accordingly, regardless of the number of conceptuses in the uterus, the plasma P4 concentration was well correlated with the regulation of conceptus growth via changes in uterine glucose levels in SOV cattle.

KW - Cattle

KW - Conceptus growth

KW - Glucose

KW - Progesterone

KW - Superovulation

UR - http://www.scopus.com/inward/record.url?scp=84869008996&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84869008996&partnerID=8YFLogxK

U2 - 10.1262/jrd.2012-079

DO - 10.1262/jrd.2012-079

M3 - Article

VL - 58

SP - 609

EP - 614

JO - Journal of Reproduction and Development

JF - Journal of Reproduction and Development

SN - 0916-8818

IS - 5

ER -