Relationship between estimated glomerular filtration rate (eGFR) and metabolic syndrome in Japanese

Nobuyuki Miyatake, Kenichi Shikata, Hirofumi Makino, Takeyuki Numata

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

We investigated the link between renal function as evaluated by estimated glomerular filtration rate (eGFR) and metabolic syndrome in Japanese. A total of 11,711 Japanese subjects, aged 20-79 years, were recruited in a cross-sectional clinical investigation. From this group, we further investigated the data on 1,576 subjects. eGFR was calculated using serum creatinine (Cr), age and sex. The diagnosis of metabolic syndrome was based on the Japanese criteria. In the first analysis, 288 men (7.8%) and 498 women (6.2%) were diagnosed with reduced eGFR (<60ml/min). eGFR was not correlated with anthropometric, body composition parameters in either sex. In the second analysis, in subjects without medications, 132 men (20.8%) and 15 women (1.6%) were diagnosed with metabolic syndrome. eGFR was lower in men with abdominal obesity and in women with hypertension was than in those without. Among Japanese not taking medications, lower eGFR may be a characteristic of men with abdominal obesity and of women with hypertension.

Original languageEnglish
Pages (from-to)203-208
Number of pages6
JournalActa medica Okayama
Volume64
Issue number3
Publication statusPublished - Jul 2010

Keywords

  • Abdominal circumference
  • Estimated glomerular filtration rate (eGFR)
  • Metabolic syndrome

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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