TY - JOUR
T1 - Relationship between bone mineral density and body composition estimated by dual-energy x-ray absorptiometry
T2 - Comparison between groups aged 20-39 and 40-59 years
AU - Hayashida, Keiichi
AU - Takeda, Yoshihiro
AU - Yatake, Hidetoshi
AU - Yamaguchi, Motoi
AU - Yamamoto, Kenyu
AU - Kuwano, Tadao
AU - Katsuda, Toshizo
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Bone mineral density (BMD) is affected by lean body mass and body weight to various degrees in the course of aging. The attempt of this study is to determine the optimal time to begin prevention of osteoporosis. In this study, female hospital employees aged 20-59 years were divided into 2 age groups, 20-39 years and 40-59 years based on age at peak BMD, and the relations of total BMD, subtotal BMD and lumbar spine BMD to lean body mass and body weight were examined in both groups. Subtotal BMD was calculated by subtracting head BMD from total BMD along with whole body measurement. While persistent positive correlations were found among all factors in the 20-39-year-old group, subtotal BMD and lumbar spine BMD were positively correlated to lean body mass in the 40-59-year-old group. Thus, lean body mass and body weight appeared to exert a profound influence on subtotal BMD in those aged 20-39 years, but lean body mass in those aged 40-59 years. Lean body mass appears to provide the best prediction of subsequent development of osteoporosis.
AB - Bone mineral density (BMD) is affected by lean body mass and body weight to various degrees in the course of aging. The attempt of this study is to determine the optimal time to begin prevention of osteoporosis. In this study, female hospital employees aged 20-59 years were divided into 2 age groups, 20-39 years and 40-59 years based on age at peak BMD, and the relations of total BMD, subtotal BMD and lumbar spine BMD to lean body mass and body weight were examined in both groups. Subtotal BMD was calculated by subtracting head BMD from total BMD along with whole body measurement. While persistent positive correlations were found among all factors in the 20-39-year-old group, subtotal BMD and lumbar spine BMD were positively correlated to lean body mass in the 40-59-year-old group. Thus, lean body mass and body weight appeared to exert a profound influence on subtotal BMD in those aged 20-39 years, but lean body mass in those aged 40-59 years. Lean body mass appears to provide the best prediction of subsequent development of osteoporosis.
KW - Age at peak bone mineral density
KW - Body weight
KW - Dual-energy X-ray absorptiometry
KW - Lean body mass
KW - Subtotal bone mineral density
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M3 - Article
C2 - 27323836
AN - SCOPUS:85047592700
VL - 61
SP - E101-E105
JO - Kobe Journal of Medical Sciences
JF - Kobe Journal of Medical Sciences
SN - 0023-2513
IS - 4
ER -