Relationship between acetaldehyde concentration in mouth air and tongue coating volume

Aya Yokoi, Takayuki Maruyama, Reiko Yamanaka, Daisuke Ekuni, Takaaki Tomofuji, Haruhiko Kashiwazaki, Yutaka Yamazaki, Manabu Morita

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Objective: Acetaldehyde is the first metabolite of ethanol and is produced in the epithelium by mucosal ALDH, while higher levels are derived from microbial oxidation of ethanol by oral microflora such as Candida species. However, it is uncertain whether acetaldehyde concentration in human breath is related to oral condition or local production of acetaldehyde by oral microflora. The aim of this pilot study was to investigate the relationship between physiological acetaldehyde concentration and oral condition in healthy volunteers. Material and Methods: Sixty-five volunteers (51 males and 14 females, aged from 20 to 87 years old) participated in the present study. Acetaldehyde concentration in mouth air was measured using a portable monitor. Oral examination, detection of oral Candida species and assessment of alcohol sensitivity were performed. Results: Acetaldehyde concentration [median (25%, 75%)] in mouth air was 170.7 (73.5, 306.3) ppb. Acetaldehyde concentration in participants with a tongue coating status score of 3 was significantly higher than in those with a score of 1 (p

Original languageEnglish
Pages (from-to)64-70
Number of pages7
JournalJournal of Applied Oral Science
Volume23
Issue number1
DOIs
Publication statusPublished - 2015

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Acetaldehyde
Tongue
Mouth
Air
Candida
Ethanol
Oral Diagnosis
Volunteers
Healthy Volunteers
Epithelium
Alcohols

Keywords

  • Acetaldehyde
  • Bacteria
  • Cross-sectional studies
  • Tongue

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Relationship between acetaldehyde concentration in mouth air and tongue coating volume. / Yokoi, Aya; Maruyama, Takayuki; Yamanaka, Reiko; Ekuni, Daisuke; Tomofuji, Takaaki; Kashiwazaki, Haruhiko; Yamazaki, Yutaka; Morita, Manabu.

In: Journal of Applied Oral Science, Vol. 23, No. 1, 2015, p. 64-70.

Research output: Contribution to journalArticle

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AU - Maruyama, Takayuki

AU - Yamanaka, Reiko

AU - Ekuni, Daisuke

AU - Tomofuji, Takaaki

AU - Kashiwazaki, Haruhiko

AU - Yamazaki, Yutaka

AU - Morita, Manabu

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N2 - Objective: Acetaldehyde is the first metabolite of ethanol and is produced in the epithelium by mucosal ALDH, while higher levels are derived from microbial oxidation of ethanol by oral microflora such as Candida species. However, it is uncertain whether acetaldehyde concentration in human breath is related to oral condition or local production of acetaldehyde by oral microflora. The aim of this pilot study was to investigate the relationship between physiological acetaldehyde concentration and oral condition in healthy volunteers. Material and Methods: Sixty-five volunteers (51 males and 14 females, aged from 20 to 87 years old) participated in the present study. Acetaldehyde concentration in mouth air was measured using a portable monitor. Oral examination, detection of oral Candida species and assessment of alcohol sensitivity were performed. Results: Acetaldehyde concentration [median (25%, 75%)] in mouth air was 170.7 (73.5, 306.3) ppb. Acetaldehyde concentration in participants with a tongue coating status score of 3 was significantly higher than in those with a score of 1 (p

AB - Objective: Acetaldehyde is the first metabolite of ethanol and is produced in the epithelium by mucosal ALDH, while higher levels are derived from microbial oxidation of ethanol by oral microflora such as Candida species. However, it is uncertain whether acetaldehyde concentration in human breath is related to oral condition or local production of acetaldehyde by oral microflora. The aim of this pilot study was to investigate the relationship between physiological acetaldehyde concentration and oral condition in healthy volunteers. Material and Methods: Sixty-five volunteers (51 males and 14 females, aged from 20 to 87 years old) participated in the present study. Acetaldehyde concentration in mouth air was measured using a portable monitor. Oral examination, detection of oral Candida species and assessment of alcohol sensitivity were performed. Results: Acetaldehyde concentration [median (25%, 75%)] in mouth air was 170.7 (73.5, 306.3) ppb. Acetaldehyde concentration in participants with a tongue coating status score of 3 was significantly higher than in those with a score of 1 (p

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