Relation of spasms and myoclonus to suppression-burst on EEG in epileptic encephalopathy in early infancy

Katsuhiro Kobayashi, T. Inoue, K. Kikumoto, Fumika Endoh, K. Miya, Makio Oka, H. Yoshinaga, Y. Ohtsuka

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Purpose: This study was intended to clarify the relation between spasms in series and a suppression-burst (SB) EEG pattern which have a common nature of repetitive bursting activity in epileptic encephalopathy in early infancy. Methods: The ictal EEG traces of spasms were temporally compressed and expanded to study the beginning and ending phases of series along with their spectral analysis in two patients with Ohtahara syndrome (OS) and one with early myoclonic encephalopathy (EME). The EEG bursts associated with myoclonus were also investigated. Results: A mutual transition was indicated between the ictal activity of spasms and the bursts in the peri-series SB on EEG. Gamma rhythm was detected in common in the ictal activity and the peri-series and interictal bursts on EEG, and also in the bursts with myoclonus. Conclusion: The relation between the ictal activity of spasms and SB on EEG was shown to be close. The generative mechanisms of spasms and myoclonus might be linked to the bursting tendency intrinsic to immature brain function.

Original languageEnglish
Pages (from-to)244-250
Number of pages7
JournalNeuropediatrics
Volume38
Issue number5
DOIs
Publication statusPublished - Oct 2007

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Myoclonus
Spasm
Brain Diseases
Electroencephalography
Stroke
Brain

Keywords

  • EEG analysis
  • Epileptic encephalopathy
  • Myoclonus
  • Spasms

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Relation of spasms and myoclonus to suppression-burst on EEG in epileptic encephalopathy in early infancy. / Kobayashi, Katsuhiro; Inoue, T.; Kikumoto, K.; Endoh, Fumika; Miya, K.; Oka, Makio; Yoshinaga, H.; Ohtsuka, Y.

In: Neuropediatrics, Vol. 38, No. 5, 10.2007, p. 244-250.

Research output: Contribution to journalArticle

Kobayashi, Katsuhiro ; Inoue, T. ; Kikumoto, K. ; Endoh, Fumika ; Miya, K. ; Oka, Makio ; Yoshinaga, H. ; Ohtsuka, Y. / Relation of spasms and myoclonus to suppression-burst on EEG in epileptic encephalopathy in early infancy. In: Neuropediatrics. 2007 ; Vol. 38, No. 5. pp. 244-250.
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