[Regulation of intracellular signal pathways via sensor proteins by oxidative stress].

Research output: Contribution to journalReview article

Abstract

It has been known that reactive oxygen species (ROS) control the enzymatic and transcriptional activity of proteins via direct modification of cysteine residues. Hence, oxidation of cysteine thiol could be a vital modulator of signal transduction pathways. These findings indicate that some proteins serve as the sensor proteins highly sensitive to ROS. In this review, I show the relationship between intracellular ROS sensor and the regulation of protein function via oxidation.

Original languageEnglish
Pages (from-to)1613-1619
Number of pages7
JournalClinical calcium
Volume23
Issue number11
Publication statusPublished - Nov 2013

ASJC Scopus subject areas

  • Medicine(all)

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