Regioselectivity of the intramolecular biaryl coupling reaction of 3-substituted phenyl 2-iodobenzoate using a palladium reagent

Kazuhiro Maeda; Takuya Matsukihira; Shumpei Saga; Yasuo Takeuchi; Takashi Harayama; Yoshikazu Horino; Hitoshi Abe

doi:10.3987/COM-13-S(S)10

Regioselectivity of the intramolecular biaryl coupling reaction of 3-substituted phenyl 2-iodobenzoate using a palladium reagent

Kazuhiro Maeda, Takuya Matsukihira, Shumpei Saga, Yasuo Takeuchi, Takashi Harayama, Yoshikazu Horino, Hitoshi Abe

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

This study investigated the regioselectivity of the intramolecular biaryl coupling reaction of the phenyl benzoate derivative which possesses a methyl or methoxy group at the meta-position of the phenoxy moiety. The type of base and the presence/absence of the phosphine ligand influenced the product ratio. A transition state model and the regioselectivity of the reaction are discussed.

Original language	English
Pages (from-to)	621-628
Number of pages	8
Journal	Heterocycles
Volume	88
Issue number	1
DOIs	https://doi.org/10.3987/COM-13-S(S)10
Publication status	Published - 2014

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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Regioselectivity of the intramolecular biaryl coupling reaction of 3-substituted phenyl 2-iodobenzoate using a palladium reagent. / Maeda, Kazuhiro; Matsukihira, Takuya; Saga, Shumpei; Takeuchi, Yasuo; Harayama, Takashi; Horino, Yoshikazu; Abe, Hitoshi.

In: Heterocycles, Vol. 88, No. 1, 2014, p. 621-628.

Research output: Contribution to journal › Article › peer-review

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author = "Kazuhiro Maeda and Takuya Matsukihira and Shumpei Saga and Yasuo Takeuchi and Takashi Harayama and Yoshikazu Horino and Hitoshi Abe",

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AU - Saga, Shumpei

AU - Takeuchi, Yasuo

AU - Harayama, Takashi

AU - Horino, Yoshikazu

AU - Abe, Hitoshi

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