Abstract
The direct arylation of benzanilide (1) possessing ether oxygen(s) in benzoyl part was examined under phosphine ligand-free conditions, which afforded ortho-product (2) and para-product (3) in very similar ratio to presence of P(o-Tol)3 conditions. This results suggest that bulkiness of palladium under phosphine-free conditions would be comparable to that of P(o-Tol)3 conditions.
| Original language | English |
|---|---|
| Pages (from-to) | 2609-2616 |
| Number of pages | 8 |
| Journal | Heterocycles |
| Volume | 81 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 2010 |
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ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry
- Pharmacology
Cite this
Regioselectivity in direct arylation of benzanilide possessing oxygen substituent in the benzoyl part using palladium without phosphine ligand. / Harayama, Takashi; Nagura, Chie; Miyagoe, Taeko; Kawata, Yuko; Abe, Hitoshi; Takeuchi, Yasuo.
In: Heterocycles, Vol. 81, No. 11, 2010, p. 2609-2616.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Regioselectivity in direct arylation of benzanilide possessing oxygen substituent in the benzoyl part using palladium without phosphine ligand
AU - Harayama, Takashi
AU - Nagura, Chie
AU - Miyagoe, Taeko
AU - Kawata, Yuko
AU - Abe, Hitoshi
AU - Takeuchi, Yasuo
PY - 2010
Y1 - 2010
N2 - The direct arylation of benzanilide (1) possessing ether oxygen(s) in benzoyl part was examined under phosphine ligand-free conditions, which afforded ortho-product (2) and para-product (3) in very similar ratio to presence of P(o-Tol)3 conditions. This results suggest that bulkiness of palladium under phosphine-free conditions would be comparable to that of P(o-Tol)3 conditions.
AB - The direct arylation of benzanilide (1) possessing ether oxygen(s) in benzoyl part was examined under phosphine ligand-free conditions, which afforded ortho-product (2) and para-product (3) in very similar ratio to presence of P(o-Tol)3 conditions. This results suggest that bulkiness of palladium under phosphine-free conditions would be comparable to that of P(o-Tol)3 conditions.
UR - http://www.scopus.com/inward/record.url?scp=79951473344&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79951473344&partnerID=8YFLogxK
U2 - 10.3987/COM-10-12040
DO - 10.3987/COM-10-12040
M3 - Article
VL - 81
SP - 2609
EP - 2616
JO - Heterocycles
JF - Heterocycles
SN - 0385-5414
IS - 11
ER -