Regioselectivity in direct arylation of benzanilide possessing oxygen substituent in the benzoyl part using palladium without phosphine ligand

Takashi Harayama, Chie Nagura, Taeko Miyagoe, Yuko Kawata, Hitoshi Abe, Yasuo Takeuchi

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

The direct arylation of benzanilide (1) possessing ether oxygen(s) in benzoyl part was examined under phosphine ligand-free conditions, which afforded ortho-product (2) and para-product (3) in very similar ratio to presence of P(o-Tol)3 conditions. This results suggest that bulkiness of palladium under phosphine-free conditions would be comparable to that of P(o-Tol)3 conditions.

Original languageEnglish
Pages (from-to)2609-2616
Number of pages8
JournalHeterocycles
Volume81
Issue number11
DOIs
Publication statusPublished - Dec 1 2010

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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