Abstract
The direct arylation of benzanilide (1) possessing ether oxygen(s) in benzoyl part was examined under phosphine ligand-free conditions, which afforded ortho-product (2) and para-product (3) in very similar ratio to presence of P(o-Tol)3 conditions. This results suggest that bulkiness of palladium under phosphine-free conditions would be comparable to that of P(o-Tol)3 conditions.
| Original language | English |
|---|---|
| Pages (from-to) | 2609-2616 |
| Number of pages | 8 |
| Journal | Heterocycles |
| Volume | 81 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - Dec 1 2010 |
ASJC Scopus subject areas
- Analytical Chemistry
- Pharmacology
- Organic Chemistry
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Harayama, T., Nagura, C., Miyagoe, T., Kawata, Y., Abe, H., & Takeuchi, Y. (2010). Regioselectivity in direct arylation of benzanilide possessing oxygen substituent in the benzoyl part using palladium without phosphine ligand. Heterocycles, 81(11), 2609-2616. https://doi.org/10.3987/COM-10-12040