Abstract
(Matrix presented) Treatment of a mixture of a terminal alkyne and an aldehyde with CrCl2 and a catalytic amount of NiCl2 and triphenylphosphine in the pre of water in DMF at 25°C gives a 1,2-disubstituted allylic alcohol regioselectively.
| Original language | English |
|---|---|
| Pages (from-to) | 653-655 |
| Number of pages | 3 |
| Journal | Organic Letters |
| Volume | 5 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Mar 6 2003 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
Fingerprint Dive into the research topics of 'Regioselective reductive coupling of alkynes and aldehydes leading to allylic alcohols'. Together they form a unique fingerprint.
Cite this
Takai, K., Sakamoto, S., & Isshiki, T. (2003). Regioselective reductive coupling of alkynes and aldehydes leading to allylic alcohols. Organic Letters, 5(5), 653-655. https://doi.org/10.1021/ol0272996