Regional variation in oral mucosal drug permeability

Yuji Kurosaki, Toshikiro Kimura

Research output: Contribution to journalReview articlepeer-review

26 Citations (Scopus)

Abstract

The purpose of this article is to review regional variation in oral mucosal drug permeability. The structure and composition of the mucosa at different sites in the oral cavity, factors affecting mucosal permeability, selection of appropriate experimental systems for studying mucosal permeability, and formulation factors including penetration enhancement relevant to the design of systems for oral mucosal delivery are reviewed.

Original languageEnglish
Pages (from-to)467-508
Number of pages42
JournalCritical Reviews in Therapeutic Drug Carrier Systems
Volume17
Issue number5
Publication statusPublished - Nov 25 2000

Keywords

  • Drug absorption
  • Oral mucosa
  • Regional variation
  • Specialized transport system

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science

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