Abstract
Regional histamine (HA) and tele-methylhistamine (t-MH) contents were determined in the rat, mouse and guinea-pig brain. The highest HA and t-MH levels were found in the hypothalamus of all species. Fairly high t-MH levels were observed in the amygdala of all species and in the guinea-pig hippocampus. The t-MH/HA ratio was higher in the regions of the telencephalon than in the diencephalon and brainstem. The cerebellum and spinal cord showed extremely low t-MH/HA ratios. These results suggest higher histaminergic neuronal activities in the hypothalamus and some regions of the telencephalon than in other parts of the brain.
| Original language | English |
|---|---|
| Pages (from-to) | 172-175 |
| Number of pages | 4 |
| Journal | Brain Research |
| Volume | 280 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Nov 28 1983 |
Keywords
- amygdala
- brain
- histamine
- histaminergic neuron
- hypothalamus
- tele-methylhistamine
ASJC Scopus subject areas
- Neuroscience(all)
- Molecular Biology
- Clinical Neurology
- Developmental Biology