Regio- and stereoselective preparation of silyl enol ethers by alkylidenation of silyl esters

Kazuhiko Takai, Yasutaka Kataoka, Takashi Okazoe, Kiitiro Utimoto

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Treatment of trimethylsilyl esters with a reagent for alkylidenation of carbonyl groups derived from 1,1-dibromoalkane, zinc, TiCl4, and TMEDA in THF gives Z-trimethylsilyl enol ethers in a regio- and stereoselective manner.

Original languageEnglish
Pages (from-to)1065-1068
Number of pages4
JournalTetrahedron Letters
Volume29
Issue number9
DOIs
Publication statusPublished - 1988
Externally publishedYes

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Ethers
Zinc
Esters
phenyllithium
titanium tetrachloride

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Regio- and stereoselective preparation of silyl enol ethers by alkylidenation of silyl esters. / Takai, Kazuhiko; Kataoka, Yasutaka; Okazoe, Takashi; Utimoto, Kiitiro.

In: Tetrahedron Letters, Vol. 29, No. 9, 1988, p. 1065-1068.

Research output: Contribution to journalArticle

Takai, Kazuhiko ; Kataoka, Yasutaka ; Okazoe, Takashi ; Utimoto, Kiitiro. / Regio- and stereoselective preparation of silyl enol ethers by alkylidenation of silyl esters. In: Tetrahedron Letters. 1988 ; Vol. 29, No. 9. pp. 1065-1068.
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