Refined balloon pulmonary angioplasty for inoperable patients with chronic thromboembolic pulmonary hypertension

Hiroki Mizoguchi, Aiko Ogawa, Mitsuru Munemasa, Hiroshi Mikouchi, Hiroshi Itoh, Hiromi Matsubara

Research output: Contribution to journalArticle

260 Citations (Scopus)

Abstract

Background-Although balloon pulmonary angioplasty (BPA) for inoperable patients with chronic thromboembolic pulmonary hypertension was first reported over a decade ago, its clinical application has been restricted because of limited efficacy and complications. We have refined the procedure of BPA to maximize its clinical efficacy. Methods and Results-Sixty-eight consecutive patients with inoperable chronic thromboembolic pulmonary hypertension underwent BPA. We evaluated pulmonary artery diameters and determined the appropriate balloon size by using intravascular ultrasound. We performed BPA in a staged fashion over multiple, separate procedures to maximize efficacy and reduce the risk of reperfusion pulmonary injury. A total of 4 (2-8) sessions were performed in each patient, and the number of vessels dilated per session was 3 (1-14). The World Health Organization functional class improved from 3 to 2 (P

Original languageEnglish
Pages (from-to)748-755
Number of pages8
JournalCirculation: Cardiovascular Interventions
Volume5
Issue number6
DOIs
Publication statusPublished - Dec 2012

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Balloon Angioplasty
Pulmonary Hypertension
Lung
Lung Injury
Reperfusion Injury
Pulmonary Artery

Keywords

  • Peripheral vascular disease
  • Pulmonary hypertension
  • Reperfusion
  • Revascularization

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Refined balloon pulmonary angioplasty for inoperable patients with chronic thromboembolic pulmonary hypertension. / Mizoguchi, Hiroki; Ogawa, Aiko; Munemasa, Mitsuru; Mikouchi, Hiroshi; Itoh, Hiroshi; Matsubara, Hiromi.

In: Circulation: Cardiovascular Interventions, Vol. 5, No. 6, 12.2012, p. 748-755.

Research output: Contribution to journalArticle

Mizoguchi, Hiroki ; Ogawa, Aiko ; Munemasa, Mitsuru ; Mikouchi, Hiroshi ; Itoh, Hiroshi ; Matsubara, Hiromi. / Refined balloon pulmonary angioplasty for inoperable patients with chronic thromboembolic pulmonary hypertension. In: Circulation: Cardiovascular Interventions. 2012 ; Vol. 5, No. 6. pp. 748-755.
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