Reduction of phosphine oxides to the corresponding phosphine derivatives in Mg/Me3SiCl/DMI system

Manabu Kuroboshi, Toshihito Kita, Asuka Aono, Toshimasa Katagiri, Seiya Kikuchi, Syoko Yamane, Hiromu Kawakubo, Hideo Tanaka

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Direct reductions of phosphine oxides to the corresponding phosphines were performed successfully by using Mg/Me3SiCl/DMI system. The reduction proceeded under mild conditions and was applicable to a wide range of phosphine oxides; triarylphosphine oxides, alkyldiarylphosphine oxides, and dialkylarylphosphine oxides gave the corresponding phosphines in good to excellent yields.

Original languageEnglish
Pages (from-to)918-920
Number of pages3
JournalTetrahedron Letters
Volume56
Issue number7
DOIs
Publication statusPublished - Feb 11 2015

Keywords

  • 1,3-Dimethyl-2-imidazolidinone
  • Magnesium
  • Phosphine
  • Phosphine oxide
  • Reduction

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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  • Cite this

    Kuroboshi, M., Kita, T., Aono, A., Katagiri, T., Kikuchi, S., Yamane, S., Kawakubo, H., & Tanaka, H. (2015). Reduction of phosphine oxides to the corresponding phosphine derivatives in Mg/Me3SiCl/DMI system. Tetrahedron Letters, 56(7), 918-920. https://doi.org/10.1016/j.tetlet.2014.12.132