Reduction of phosphine oxides to the corresponding phosphine derivatives in Mg/Me3SiCl/DMI system

Manabu Kuroboshi, Toshihito Kita, Asuka Aono, Toshimasa Katagiri, Seiya Kikuchi, Syoko Yamane, Hiromu Kawakubo, Hideo Tanaka

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Direct reductions of phosphine oxides to the corresponding phosphines were performed successfully by using Mg/Me3SiCl/DMI system. The reduction proceeded under mild conditions and was applicable to a wide range of phosphine oxides; triarylphosphine oxides, alkyldiarylphosphine oxides, and dialkylarylphosphine oxides gave the corresponding phosphines in good to excellent yields.

Original languageEnglish
Pages (from-to)918-920
Number of pages3
JournalTetrahedron Letters
Volume56
Issue number7
DOIs
Publication statusPublished - Feb 11 2015

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phosphine
Oxides
Derivatives
Phosphines

Keywords

  • 1,3-Dimethyl-2-imidazolidinone
  • Magnesium
  • Phosphine
  • Phosphine oxide
  • Reduction

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Reduction of phosphine oxides to the corresponding phosphine derivatives in Mg/Me3SiCl/DMI system. / Kuroboshi, Manabu; Kita, Toshihito; Aono, Asuka; Katagiri, Toshimasa; Kikuchi, Seiya; Yamane, Syoko; Kawakubo, Hiromu; Tanaka, Hideo.

In: Tetrahedron Letters, Vol. 56, No. 7, 11.02.2015, p. 918-920.

Research output: Contribution to journalArticle

Kuroboshi, M, Kita, T, Aono, A, Katagiri, T, Kikuchi, S, Yamane, S, Kawakubo, H & Tanaka, H 2015, 'Reduction of phosphine oxides to the corresponding phosphine derivatives in Mg/Me3SiCl/DMI system', Tetrahedron Letters, vol. 56, no. 7, pp. 918-920. https://doi.org/10.1016/j.tetlet.2014.12.132
Kuroboshi, Manabu ; Kita, Toshihito ; Aono, Asuka ; Katagiri, Toshimasa ; Kikuchi, Seiya ; Yamane, Syoko ; Kawakubo, Hiromu ; Tanaka, Hideo. / Reduction of phosphine oxides to the corresponding phosphine derivatives in Mg/Me3SiCl/DMI system. In: Tetrahedron Letters. 2015 ; Vol. 56, No. 7. pp. 918-920.
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AU - Kawakubo, Hiromu

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