Abstract
Background: With the improvement in sanitation and hygiene, the incidence of hepatitis A virus (HAV) infection has declined, and its seroprevalence among Japanese people has been reduced. Universal HAV vaccination is yet to be implemented in Japan, and the healthcare workers (HCWs) are at higher risks of acquiring this infection. We herein report the seroepidemiology of HAV infection among HCWs at Osaka University Hospital. Methods: Between September and October 2017, we collected serum samples submitted to our laboratory for HCWs health examination and tested for the anti-HAV antibody. Results: Overall HAV seropositivity rate was 5.1% (22/436 samples). The seroprevalence was higher among those in the twenties (6.0%) and thirties (8.0%), compared to older age groups. Conclusions: In this age of internationalization, the decreasing immunity for HAV places HCWs at risk of developing the disease. As a preventive measure against occupational infection, HAV vaccination may be needed for Japanese HCWs.
| Original language | English |
|---|---|
| Pages (from-to) | 1791-1793 |
| Number of pages | 3 |
| Journal | Clinical Laboratory |
| Volume | 64 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Jan 1 2018 |
| Externally published | Yes |
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Keywords
- Hepatitis A
- Occupational infection
- Vaccination
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Reduced seroprevalence of hepatitis A virus among Japanese healthcare workers as a risk factor for occupational infection. / Yoshioka, Nori; Deguchi, Matsuo; Hagiya, Hideharu; Kagita, Masanori; Tomono, Kazunori.
In: Clinical Laboratory, Vol. 64, No. 10, 01.01.2018, p. 1791-1793.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Reduced seroprevalence of hepatitis A virus among Japanese healthcare workers as a risk factor for occupational infection
AU - Yoshioka, Nori
AU - Deguchi, Matsuo
AU - Hagiya, Hideharu
AU - Kagita, Masanori
AU - Tomono, Kazunori
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Background: With the improvement in sanitation and hygiene, the incidence of hepatitis A virus (HAV) infection has declined, and its seroprevalence among Japanese people has been reduced. Universal HAV vaccination is yet to be implemented in Japan, and the healthcare workers (HCWs) are at higher risks of acquiring this infection. We herein report the seroepidemiology of HAV infection among HCWs at Osaka University Hospital. Methods: Between September and October 2017, we collected serum samples submitted to our laboratory for HCWs health examination and tested for the anti-HAV antibody. Results: Overall HAV seropositivity rate was 5.1% (22/436 samples). The seroprevalence was higher among those in the twenties (6.0%) and thirties (8.0%), compared to older age groups. Conclusions: In this age of internationalization, the decreasing immunity for HAV places HCWs at risk of developing the disease. As a preventive measure against occupational infection, HAV vaccination may be needed for Japanese HCWs.
AB - Background: With the improvement in sanitation and hygiene, the incidence of hepatitis A virus (HAV) infection has declined, and its seroprevalence among Japanese people has been reduced. Universal HAV vaccination is yet to be implemented in Japan, and the healthcare workers (HCWs) are at higher risks of acquiring this infection. We herein report the seroepidemiology of HAV infection among HCWs at Osaka University Hospital. Methods: Between September and October 2017, we collected serum samples submitted to our laboratory for HCWs health examination and tested for the anti-HAV antibody. Results: Overall HAV seropositivity rate was 5.1% (22/436 samples). The seroprevalence was higher among those in the twenties (6.0%) and thirties (8.0%), compared to older age groups. Conclusions: In this age of internationalization, the decreasing immunity for HAV places HCWs at risk of developing the disease. As a preventive measure against occupational infection, HAV vaccination may be needed for Japanese HCWs.
KW - Hepatitis A
KW - Occupational infection
KW - Vaccination
UR - http://www.scopus.com/inward/record.url?scp=85055080572&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85055080572&partnerID=8YFLogxK
U2 - 10.7754/Clin.Lab.2018.180518
DO - 10.7754/Clin.Lab.2018.180518
M3 - Article
C2 - 30336521
AN - SCOPUS:85055080572
VL - 64
SP - 1791
EP - 1793
JO - Clinical Laboratory
JF - Clinical Laboratory
SN - 1433-6510
IS - 10
ER -