Red and near infra-red signaling: Hypothesis and perspectives

Vladimir D. Kreslavski, Irina R. Fomina, Dmitry A. Los, Robert Carpentier, Vladimir V. Kuznetsov, Suleyman I. Allakhverdiev

Research output: Contribution to journalReview articlepeer-review

36 Citations (Scopus)


The review covers some of the proposed cellular photoreceptors responsible for the effect of red and near infra-red (NIR) light on mammalian cells, including cytochrome-c-oxidase, photoactive porphyrins, flavoproteins, and molecular oxygen. We do not discuss the clinical studies but consider animal models, especially fibroblasts. Several key hypotheses such as mitochondria signaling and free-radical conception of the effects of red light and NIR light based on the changes in redox properties of photoreceptor molecules as well as membrane conception are examined. Special attention is paid to common mechanisms of light signaling in mammalian and plant organisms.

Original languageEnglish
Pages (from-to)190-203
Number of pages14
JournalJournal of Photochemistry and Photobiology C: Photochemistry Reviews
Issue number3
Publication statusPublished - Sep 2012


  • Cytochrome-c-oxidase
  • Flavoproteins
  • Free radicals
  • Near infra-red light
  • Photoactive porphyrins
  • Photoreceptors
  • Red light
  • Signaling systems

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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