Recurrent idiopathic iridocyclitis after autologous peripheral blood stem-cell transplantation followed by G-CSF administration for acute lymphoblastic leukemia

J. Tsuchiyama, K. Imajo, N. Sakaguchi, Tadashi Yoshino, N. Suzaki, E. Kondo, N. Kawata, K. Okada, T. Maeda, Y. Tomiyama, T. Tsubota

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Abstract

We describe a patient who experienced a recurrence of idiopathic iridocyclitis on day 12 after autologous peripheral blood stem-cell transplantation (auto-PBSCT) followed by G-CSF administration for acute lymphoblastic leukemia (ALL). Autologous SCT has been reported to be effective and safe in achieving dose intensification of chemotherapeutic drugs for the treatment of hematopoietic malignancies, but its therapeutic effect on autoimmune diseases is not definite. The findings from the present case suggest that auto-PBSCT followed by G-CSF administration for patients with a history of some kind of autoimmune disorders may induce exacerbation or recurrence of its symptoms after hematopoietic recovery.

Original languageEnglish
Pages (from-to)269-271
Number of pages3
JournalAnnals of Hematology
Volume79
Issue number5
DOIs
Publication statusPublished - Sep 5 1999

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Keywords

  • ALL
  • Auto-PBSCT
  • Recurrent idiopathic iridocyclitis

ASJC Scopus subject areas

  • Hematology

Cite this

Tsuchiyama, J., Imajo, K., Sakaguchi, N., Yoshino, T., Suzaki, N., Kondo, E., Kawata, N., Okada, K., Maeda, T., Tomiyama, Y., & Tsubota, T. (1999). Recurrent idiopathic iridocyclitis after autologous peripheral blood stem-cell transplantation followed by G-CSF administration for acute lymphoblastic leukemia. Annals of Hematology, 79(5), 269-271. https://doi.org/10.1007/s002770050591