Recurrent cancer of the parotid gland: How well does salvage surgery work for locoregional failure?

Kenya Kobayashi, Kazunari Nakao, Masafumi Yoshida, Mizuo Ando, Yasuhiro Ebihara, Takahiro Asakage, Tatsuya Yamasoba

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Purpose: Many articles have discussed the clinical features of previously untreated parotid cancer, but the clinical characteristics and treatment of recurrent parotid cancer have not yet been fully described. Materials: We retrospectively reviewed 20 patients with recurrent parotid cancer and analyzed the therapeutic strategies and the prognostic factors. Results: Twelve patients (60%) underwent definitive surgery, including 3 who underwent skull base surgery. The 5-year overall survival (OS) and 5-year disease-free survival (DFS) in the surgery group were 66.7 and 64.1%. In the definitive surgery group, the presence of lymph node metastasis and high-grade malignant histopathology were associated with a poor prognosis (p < 0.01). On the other hand, the presence of facial palsy at presentation, the surgical margin, the time of relapse and the T stage did not affect the DFS in our series. Conclusions: The results suggest that aggressive definitive surgery may be justified for the treatment of recurrent parotid cancer. The presence of lymph node metastasis and the histopathological malignancy grade are poor prognostic factors for OS and DFS.

Original languageEnglish
Pages (from-to)239-243
Number of pages5
JournalORL
Volume71
Issue number5
DOIs
Publication statusPublished - Nov 2009
Externally publishedYes

Keywords

  • Histopathological grade
  • Lymph node metastasis
  • Recurrent parotid cancer

ASJC Scopus subject areas

  • Otorhinolaryngology

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