Recurrence after radiotherapy for gastric mucosa-associated lymphoid tissue (MALT) lymphoma with trisomy 18

Hisashi Ishikawa; Masaya Iwamuro; Hiroyuki Okada; Keisuke Hori; Masahide Kita; Seiji Kawano; Yoshiro Kawahara; Takehiro Tanaka; Eisei Kondo; Tadashi Yoshino; Kazuhide Yamamoto

doi:10.2169/internalmedicine.54.3784

Recurrence after radiotherapy for gastric mucosa-associated lymphoid tissue (MALT) lymphoma with trisomy 18

Hisashi Ishikawa, Masaya Iwamuro, Hiroyuki Okada, Keisuke Hori, Masahide Kita, Seiji Kawano, Yoshiro Kawahara, Takehiro Tanaka, Eisei Kondo, Tadashi Yoshino, Kazuhide Yamamoto

Research output: Contribution to journal › Article

3 Citations (Scopus)

Abstract

A 36-year-old Japanese woman presented with extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the stomach. The gastric lesions only partially improved after eradication therapy for Helicobacter pylori. A fluorescence in situ hybridization analysis revealed no fusion genes of API2-MALT1, although trisomy of chromosome 18 was identified. Radiation therapy was initiated to treat the gastric lymphoma lesions, resulting in complete remission. However, MALT lymphoma recurred in the stomach 16 months later. This case indicates that intensive follow-up is required for MALT lymphoma associated with chromosomal aberrations in order to detect early relapse.

Original language	English
Pages (from-to)	911-916
Number of pages	6
Journal	Internal Medicine
Volume	54
Issue number	8
DOIs	https://doi.org/10.2169/internalmedicine.54.3784
Publication status	Published - Jan 1 2015

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Keywords

Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue
Gastric lymphoma
MALT lymphoma
Trisomy 18

ASJC Scopus subject areas

Internal Medicine

Cite this

Ishikawa, H., Iwamuro, M., Okada, H., Hori, K., Kita, M., Kawano, S., Kawahara, Y., Tanaka, T., Kondo, E., Yoshino, T., & Yamamoto, K. (2015). Recurrence after radiotherapy for gastric mucosa-associated lymphoid tissue (MALT) lymphoma with trisomy 18. Internal Medicine, 54(8), 911-916. https://doi.org/10.2169/internalmedicine.54.3784

Recurrence after radiotherapy for gastric mucosa-associated lymphoid tissue (MALT) lymphoma with trisomy 18. / Ishikawa, Hisashi; Iwamuro, Masaya ; Okada, Hiroyuki; Hori, Keisuke; Kita, Masahide; Kawano, Seiji ; Kawahara, Yoshiro ; Tanaka, Takehiro; Kondo, Eisei; Yoshino, Tadashi; Yamamoto, Kazuhide.

In: Internal Medicine, Vol. 54, No. 8, 01.01.2015, p. 911-916.

Research output: Contribution to journal › Article

Ishikawa, Hisashi ; Iwamuro, Masaya ; Okada, Hiroyuki ; Hori, Keisuke ; Kita, Masahide ; Kawano, Seiji ; Kawahara, Yoshiro ; Tanaka, Takehiro ; Kondo, Eisei ; Yoshino, Tadashi ; Yamamoto, Kazuhide. / Recurrence after radiotherapy for gastric mucosa-associated lymphoid tissue (MALT) lymphoma with trisomy 18. In: Internal Medicine. 2015 ; Vol. 54, No. 8. pp. 911-916.

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10.2169/internalmedicine.54.3784