Abstract
A 36-year-old Japanese woman presented with extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the stomach. The gastric lesions only partially improved after eradication therapy for Helicobacter pylori. A fluorescence in situ hybridization analysis revealed no fusion genes of API2-MALT1, although trisomy of chromosome 18 was identified. Radiation therapy was initiated to treat the gastric lymphoma lesions, resulting in complete remission. However, MALT lymphoma recurred in the stomach 16 months later. This case indicates that intensive follow-up is required for MALT lymphoma associated with chromosomal aberrations in order to detect early relapse.
| Original language | English |
|---|---|
| Pages (from-to) | 911-916 |
| Number of pages | 6 |
| Journal | Internal Medicine |
| Volume | 54 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 2015 |
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Keywords
- Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue
- Gastric lymphoma
- MALT lymphoma
- Trisomy 18
ASJC Scopus subject areas
- Internal Medicine
- Medicine(all)
Cite this
Recurrence after radiotherapy for gastric mucosa-associated lymphoid tissue (MALT) lymphoma with trisomy 18. / Ishikawa, Hisashi; Iwamuro, Masaya; Okada, Hiroyuki; Hori, Keisuke; Kita, Masahide; Kawano, Seiji; Kawahara, Yoshiro; Tanaka, Takehiro; Kondo, Eisei; Yoshino, Tadashi; Yamamoto, Kazuhide.
In: Internal Medicine, Vol. 54, No. 8, 2015, p. 911-916.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Recurrence after radiotherapy for gastric mucosa-associated lymphoid tissue (MALT) lymphoma with trisomy 18
AU - Ishikawa, Hisashi
AU - Iwamuro, Masaya
AU - Okada, Hiroyuki
AU - Hori, Keisuke
AU - Kita, Masahide
AU - Kawano, Seiji
AU - Kawahara, Yoshiro
AU - Tanaka, Takehiro
AU - Kondo, Eisei
AU - Yoshino, Tadashi
AU - Yamamoto, Kazuhide
PY - 2015
Y1 - 2015
N2 - A 36-year-old Japanese woman presented with extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the stomach. The gastric lesions only partially improved after eradication therapy for Helicobacter pylori. A fluorescence in situ hybridization analysis revealed no fusion genes of API2-MALT1, although trisomy of chromosome 18 was identified. Radiation therapy was initiated to treat the gastric lymphoma lesions, resulting in complete remission. However, MALT lymphoma recurred in the stomach 16 months later. This case indicates that intensive follow-up is required for MALT lymphoma associated with chromosomal aberrations in order to detect early relapse.
AB - A 36-year-old Japanese woman presented with extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the stomach. The gastric lesions only partially improved after eradication therapy for Helicobacter pylori. A fluorescence in situ hybridization analysis revealed no fusion genes of API2-MALT1, although trisomy of chromosome 18 was identified. Radiation therapy was initiated to treat the gastric lymphoma lesions, resulting in complete remission. However, MALT lymphoma recurred in the stomach 16 months later. This case indicates that intensive follow-up is required for MALT lymphoma associated with chromosomal aberrations in order to detect early relapse.
KW - Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue
KW - Gastric lymphoma
KW - MALT lymphoma
KW - Trisomy 18
UR - http://www.scopus.com/inward/record.url?scp=84927633670&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84927633670&partnerID=8YFLogxK
U2 - 10.2169/internalmedicine.54.3784
DO - 10.2169/internalmedicine.54.3784
M3 - Article
C2 - 25876571
AN - SCOPUS:84927633670
VL - 54
SP - 911
EP - 916
JO - Internal Medicine
JF - Internal Medicine
SN - 0918-2918
IS - 8
ER -