Reconstruction of great vessel for patients with advanced lung cancer or malignant mediastinal tumor

H. Tanaka, S. Miyoshi, A. Okumura, H. E. Yoon, S. Takeda, M. Minami, H. Hirabayashi, K. Nakahara, H. Matsuda

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Fifteen lung cancer (LC) and 11 malignant mediastinal tumor (MMT) patients who received surgical treatment in association with a reconstruction of great vessel from 1981 to 1997 were retrospectively reviewed. The aorta was resected in 7 (AO group) of 15 LC patients and the superior vena cava in the remaining 8 patients (SVC group). Pathological examination revealed actual tumor invasion in one (14%) of AO group and 6 (75%) of SVC group. In 7 p-T4 patients, 6 (85.7%) were p-N2 or N3 diseases. Five of the 6 patients belonged to SVC group and one to AO group. Five-year survival rate was 10% in all LC patients, 20% in p-T3 patients, 0% in p-T4 cancers, 50% in p-N0 patients and 0% in p-N2 or N3 patients. Eleven MMT patients included 5 thymomas, 2 thymic cancers and 4 germ cell tumors. SVC was resected and replaced with ringed PTFE graft in all patients. Invasion of vessel wall was diagnosed pathologically in 10 of 11 patients. Fifteen-year survival rate was 60% in 5 thymoma patients but 4 of whom had distant metastasis. Five-year survival rate was 50% in thymic cancers and 0% in germ cell tumors. Since the prognosis of LC and MMT patients who have tumor invasion of the great vessel is very poor, induction therapy based on preoperatively pathological diagnosis is recommended.

Original languageEnglish
Pages (from-to)19-24
Number of pages6
JournalKyobu geka. The Japanese journal of thoracic surgery
Volume52
Issue number1
Publication statusPublished - 1999
Externally publishedYes

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Lung Neoplasms
Neoplasms
Thymus Neoplasms
Thymoma
Survival Rate
Germ Cell and Embryonal Neoplasms
Superior Vena Cava
Polytetrafluoroethylene
Aorta
Neoplasm Metastasis
Transplants

Cite this

Tanaka, H., Miyoshi, S., Okumura, A., Yoon, H. E., Takeda, S., Minami, M., ... Matsuda, H. (1999). Reconstruction of great vessel for patients with advanced lung cancer or malignant mediastinal tumor. Kyobu geka. The Japanese journal of thoracic surgery, 52(1), 19-24.

Reconstruction of great vessel for patients with advanced lung cancer or malignant mediastinal tumor. / Tanaka, H.; Miyoshi, S.; Okumura, A.; Yoon, H. E.; Takeda, S.; Minami, M.; Hirabayashi, H.; Nakahara, K.; Matsuda, H.

In: Kyobu geka. The Japanese journal of thoracic surgery, Vol. 52, No. 1, 1999, p. 19-24.

Research output: Contribution to journalArticle

Tanaka, H, Miyoshi, S, Okumura, A, Yoon, HE, Takeda, S, Minami, M, Hirabayashi, H, Nakahara, K & Matsuda, H 1999, 'Reconstruction of great vessel for patients with advanced lung cancer or malignant mediastinal tumor', Kyobu geka. The Japanese journal of thoracic surgery, vol. 52, no. 1, pp. 19-24.
Tanaka, H. ; Miyoshi, S. ; Okumura, A. ; Yoon, H. E. ; Takeda, S. ; Minami, M. ; Hirabayashi, H. ; Nakahara, K. ; Matsuda, H. / Reconstruction of great vessel for patients with advanced lung cancer or malignant mediastinal tumor. In: Kyobu geka. The Japanese journal of thoracic surgery. 1999 ; Vol. 52, No. 1. pp. 19-24.
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