Recent trends in the initial therapy for newly diagnosed prostate cancer in Japan

Mizuki Onozawa, Shiro Hinotsu, Taiji Tsukamoto, Mototsugu Oya, Osamu Ogawa, Tadaichi Kitamura, Kazuhiro Suzuki, Seiji Naito, Mikio Namiki, Kazuo Nishimura, Yoshihiko Hirao, Hideyuki Akaza

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

OBJECTIVE: The objective of the present study was to investigate the trends over time in the initial treatment of prostate cancer in Japan.

METHODS: A total of 8291 patients with newly diagnosed prostate cancer whose treatment started in 2010 were registered in a multi-institutional observational study undertaken nationwide across Japan by the Japan Prostate Cancer Study Group. Each patient's background characteristics and initial treatment were recorded.

RESULTS: The median age at diagnosis was 71 years. The proportion of T1c disease was 40.5% and that of M1 disease was 10.4%. The prostate-specific antigen level was

CONCLUSION: Compared with previous Japanese studies, radiation use was increased by ∼10%. This increased proportion of radiation use was a typical trend in initial therapy for newly diagnosed prostate cancer cases in Japan. Although androgen depletion therapy use was decreased, it was selected in a high proportion of the patients irrespective of the disease stage.

Original languageEnglish
Pages (from-to)969-981
Number of pages13
JournalJapanese Journal of Clinical Oncology
Volume44
Issue number10
DOIs
Publication statusPublished - Oct 1 2014

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Prostatic Neoplasms
Japan
Radiation
Therapeutics
Prostate-Specific Antigen
Androgens
Observational Studies

Keywords

  • androgen depletion therapy
  • J-CaP
  • prostate cancer
  • prostatectomy
  • radiation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Onozawa, M., Hinotsu, S., Tsukamoto, T., Oya, M., Ogawa, O., Kitamura, T., ... Akaza, H. (2014). Recent trends in the initial therapy for newly diagnosed prostate cancer in Japan. Japanese Journal of Clinical Oncology, 44(10), 969-981. https://doi.org/10.1093/jjco/hyu104

Recent trends in the initial therapy for newly diagnosed prostate cancer in Japan. / Onozawa, Mizuki; Hinotsu, Shiro; Tsukamoto, Taiji; Oya, Mototsugu; Ogawa, Osamu; Kitamura, Tadaichi; Suzuki, Kazuhiro; Naito, Seiji; Namiki, Mikio; Nishimura, Kazuo; Hirao, Yoshihiko; Akaza, Hideyuki.

In: Japanese Journal of Clinical Oncology, Vol. 44, No. 10, 01.10.2014, p. 969-981.

Research output: Contribution to journalArticle

Onozawa, M, Hinotsu, S, Tsukamoto, T, Oya, M, Ogawa, O, Kitamura, T, Suzuki, K, Naito, S, Namiki, M, Nishimura, K, Hirao, Y & Akaza, H 2014, 'Recent trends in the initial therapy for newly diagnosed prostate cancer in Japan', Japanese Journal of Clinical Oncology, vol. 44, no. 10, pp. 969-981. https://doi.org/10.1093/jjco/hyu104
Onozawa, Mizuki ; Hinotsu, Shiro ; Tsukamoto, Taiji ; Oya, Mototsugu ; Ogawa, Osamu ; Kitamura, Tadaichi ; Suzuki, Kazuhiro ; Naito, Seiji ; Namiki, Mikio ; Nishimura, Kazuo ; Hirao, Yoshihiko ; Akaza, Hideyuki. / Recent trends in the initial therapy for newly diagnosed prostate cancer in Japan. In: Japanese Journal of Clinical Oncology. 2014 ; Vol. 44, No. 10. pp. 969-981.
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