Recent progress in the synthetic study of an antitumor marine macrolide aplyronine A and related molecules

Ichiro Hayakawa, Hideo Kigoshi Kigoshi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Aplyronine A is a potent antitumor marine macrolide. The unique molecular structures of aplyronine A and its congeners, in conjunction with their potent biological activities, have made them attractive synthetic targets. This review discusses recent progress in the development of efficient routes to the synthesis of aplyronines and the related molecules.

Original languageEnglish
Pages (from-to)1137-1155
Number of pages19
JournalHeterocycles
Volume91
Issue number6
DOIs
Publication statusPublished - 2015

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Macrolides
Molecules
Bioactivity
Molecular Structure
Molecular structure
aplyronine A

ASJC Scopus subject areas

  • Analytical Chemistry
  • Organic Chemistry
  • Pharmacology

Cite this

Recent progress in the synthetic study of an antitumor marine macrolide aplyronine A and related molecules. / Hayakawa, Ichiro; Kigoshi, Hideo Kigoshi.

In: Heterocycles, Vol. 91, No. 6, 2015, p. 1137-1155.

Research output: Contribution to journalArticle

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