Recent improvement in lung cancer screening

A comparison of the results carried out in two different time periods

Takuji Kitajima, Kenji Nishii, Hiroshi Ueoka, Takuo Shibayama, Kenichi Gemba, Tsuyoshi Kodani, Katsuyuki Kiura, Masahiro Tabata, Katsuyuki Hotta, Mitsune Tanimoto, Tomotaka Sobue

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

To evaluate recent improvements in lung cancer screening, we compared the results of recently conducted lung cancer screening with those of a previous screening. This study compared the survival of lung cancer patients detected by lung cancer screening conducted between 1976 and 1984 (early period) with that conducted between 1989 and 1997 (late period). Two hundred seventy-six patients with lung cancer were detected in the early period and 541 patients with lung cancer were detected in the late period. The median survival time (late: 49.8 vs. early: 27.8 months) and the 5-year survival rate (late: 47.8 vs. early: 34.8%) of the patients with lung cancer detected in the late period were significantly better than those in the early period (p = 0.0054). Among patients undergoing resection, the proportion of pathological stage I patients in the late period was significantly higher than that in the early period (late: 60.8 vs. early: 54.9%, p = 0.005). Multivariate analysis showed that the screening time period was a significant prognostic factor (hazard ratio = 0.685, 95% confidence interval: 0.563-0.832, p = 0.0002). These results were consistent with the findings of case-control studies of lung cancer screening programs in the late period recently conducted in Japan, which also showed a greater efficacy for screening than for previous case-control studies in the early period. Copyright

Original languageEnglish
Pages (from-to)173-179
Number of pages7
JournalActa Medica Okayama
Volume60
Issue number3
Publication statusPublished - 2006

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Early Detection of Cancer
Lung Neoplasms
Screening
Case-Control Studies
Survival
Hazards
Japan
Multivariate Analysis
Survival Rate
Confidence Intervals

Keywords

  • Lung cancer
  • Lung cancer mortality
  • Screening
  • Survival

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Kitajima, T., Nishii, K., Ueoka, H., Shibayama, T., Gemba, K., Kodani, T., ... Sobue, T. (2006). Recent improvement in lung cancer screening: A comparison of the results carried out in two different time periods. Acta Medica Okayama, 60(3), 173-179.

Recent improvement in lung cancer screening : A comparison of the results carried out in two different time periods. / Kitajima, Takuji; Nishii, Kenji; Ueoka, Hiroshi; Shibayama, Takuo; Gemba, Kenichi; Kodani, Tsuyoshi; Kiura, Katsuyuki; Tabata, Masahiro; Hotta, Katsuyuki; Tanimoto, Mitsune; Sobue, Tomotaka.

In: Acta Medica Okayama, Vol. 60, No. 3, 2006, p. 173-179.

Research output: Contribution to journalArticle

Kitajima, T, Nishii, K, Ueoka, H, Shibayama, T, Gemba, K, Kodani, T, Kiura, K, Tabata, M, Hotta, K, Tanimoto, M & Sobue, T 2006, 'Recent improvement in lung cancer screening: A comparison of the results carried out in two different time periods', Acta Medica Okayama, vol. 60, no. 3, pp. 173-179.
Kitajima T, Nishii K, Ueoka H, Shibayama T, Gemba K, Kodani T et al. Recent improvement in lung cancer screening: A comparison of the results carried out in two different time periods. Acta Medica Okayama. 2006;60(3):173-179.
Kitajima, Takuji ; Nishii, Kenji ; Ueoka, Hiroshi ; Shibayama, Takuo ; Gemba, Kenichi ; Kodani, Tsuyoshi ; Kiura, Katsuyuki ; Tabata, Masahiro ; Hotta, Katsuyuki ; Tanimoto, Mitsune ; Sobue, Tomotaka. / Recent improvement in lung cancer screening : A comparison of the results carried out in two different time periods. In: Acta Medica Okayama. 2006 ; Vol. 60, No. 3. pp. 173-179.
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