Recent developments in synthetic strategies toward highly oxygenated steroids cardenolides

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Polyoxygenated steroids cardenolides, typified by ouabagenin, possess a broad spectrum of biological activity such as inotropic activity. Due to their unique structure, including unusual cis-fused A/B- and C/D ring junction, and a number of β-configured oxygenated functional group, they have been an attractive target in chemical synthesis. In this review, recent developments in the practical synthetic strategies toward these cardenolides are described.

Original languageEnglish
Pages (from-to)253-254
Number of pages2
JournalYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
Volume75
Issue number3
DOIs
Publication statusPublished - Jan 1 2017
Externally publishedYes

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Cardenolides
Steroids
Bioactivity
Functional groups

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

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