Recent advances in hydrogen research as a therapeutic medical gas

Chien Sheng Huang, Tomohiro Kawamura, Yoshiya Toyoda, Atsunori Nakao

Research output: Contribution to journalReview article

184 Citations (Scopus)

Abstract

Recent basic and clinical research has revealed that hydrogen is an important physiological regulatory factor with antioxidant, anti-inflammatory and anti-apoptotic protective effects on cells and organs. Therapeutic hydrogen has been applied by different delivery methods including straightforward inhalation, drinking hydrogen dissolved in water and injection with hydrogen-saturated saline. This review summarizes currently available data regarding the protective role of hydrogen, provides an outline of recent advances in research on the use of hydrogen as a therapeutic medical gas in diverse models of disease and discusses the feasibility of hydrogen as a therapeutic strategy. It is not an overstatement to say that hydrogen's impact on therapeutic and preventive medicine could be enormous in the future.

Original languageEnglish
Pages (from-to)971-982
Number of pages12
JournalFree Radical Research
Volume44
Issue number9
DOIs
Publication statusPublished - Sep 1 2010
Externally publishedYes

Keywords

  • Molecular hydrogen
  • antioxidant therapy
  • radical oxygen species

ASJC Scopus subject areas

  • Biochemistry

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