Reaction of fluorinated ketones with dialkyl phosphites: An efficient and selective transformation of aryl F-alkyl ketones into dialkyl aryl (F-alkyl)methyl phosphates

Manabu Kuroboshi, Takashi Ishihara, Teiichi Ando

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Aryl F-alkyl ketones smoothly reacted with a variety of dialkyl phosphites in the presence (or absence) of a tertiary amine to give the corresponding dialkyl aryl(F-alkyl)methyl phosphates in high yields. The reaction of methyl F-phenyl ketone with the sodium salt of diethyl phosphite afforded a good yield of diethyl 1-(Fphenyl)ethyl phosphate. This reaction offers a new supplemental route to various polyfluorinated esters of phosphoric acid. A possible mechanism for the reaction is also described briefly.

Original languageEnglish
Pages (from-to)293-298
Number of pages6
JournalJournal of Fluorine Chemistry
Volume39
Issue number2
DOIs
Publication statusPublished - May 1988
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Environmental Chemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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