Reaction of 1,2,3,4-Tetrahydroquinazolin-4-ones with Acid Anhydride. III

Masatoshi Yamato, Jiroh Horiuchi, Yasuo Takeuchi

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The reaction of C2-substituted 1,2,3,4-tetrahydroquinazolin-4-ones (1) with acetic anhydride and pyridine was carried out in order to elucidate the effect of the C2-substituent. It was found that the various types of reactions occurred depending on the kind and number of C2-substituents of 1,2,3,4-tetrahydroquinazolin-4-ones (1).

Original languageEnglish
Pages (from-to)3124-3129
Number of pages6
JournalChemical and Pharmaceutical Bulletin
Volume29
Issue number11
DOIs
Publication statusPublished - Jan 1 1981

Keywords

  • 1,4-dihydroquinolin-4-ones
  • 4-quinazolinones
  • acetic anhydride
  • acylation
  • substituent effect

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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