Rat small intestinal transplantation: A comparison of the cuff and hand-suture methods

Atsunori Nakao, Naoshi Mitsuoka, Sun Don Shen, Noriaki Tanaka, Eiji Kobayashi

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

The rat model is ideal for investigating various reactions to small intestinal transplantation (SIT). The conventional surgical model (hand-suture method), however, requires microsurgical techniques and remains difficult for beginners to perform at a high success rate. We have employed the SIT model using the cuff method, by which the vessels are anastomosed without sutures. All of the fellows who used the hand-suture models needed over 8 ± 5.8 months until they achieved a 70% success rate. In contrast, the fellows employing the cuff method mastered SIT models after 6 weeks' practice. The cuff technique is a simplified and quickly mastered alternative to the hand-suture method that may be desirable for researchers who wish to apply the method to SIT experiments and whose primary purpose is not microsurgery.

Original languageEnglish
Pages (from-to)259-264
Number of pages6
JournalActa medica Okayama
Volume54
Issue number6
Publication statusPublished - Dec 1 2000

Keywords

  • Cuff technique
  • Rat model
  • Small intestinal transplantation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'Rat small intestinal transplantation: A comparison of the cuff and hand-suture methods'. Together they form a unique fingerprint.

Cite this