Rat small intestinal transplantation: A comparison of the cuff and hand-suture methods

Atsunori Nakao, Naoshi Mitsuoka, Sun Don Shen, Noriaki Tanaka, Eiji Kobayashi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The rat model is ideal for investigating various reactions to small intestinal transplantation (SIT). The conventional surgical model (hand-suture method), however, requires microsurgical techniques and remains difficult for beginners to perform at a high success rate. We have employed the SIT model using the cuff method, by which the vessels are anastomosed without sutures. All of the fellows who used the hand-suture models needed over 8 ± 5.8 months until they achieved a 70% success rate. In contrast, the fellows employing the cuff method mastered SIT models after 6 weeks' practice. The cuff technique is a simplified and quickly mastered alternative to the hand-suture method that may be desirable for researchers who wish to apply the method to SIT experiments and whose primary purpose is not microsurgery.

Original languageEnglish
Pages (from-to)259-264
Number of pages6
JournalActa Medica Okayama
Volume54
Issue number6
Publication statusPublished - 2000

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Sutures
Rats
Hand
Transplantation
Anatomic Models
Microsurgery
Research Personnel
Experiments

Keywords

  • Cuff technique
  • Rat model
  • Small intestinal transplantation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Nakao, A., Mitsuoka, N., Shen, S. D., Tanaka, N., & Kobayashi, E. (2000). Rat small intestinal transplantation: A comparison of the cuff and hand-suture methods. Acta Medica Okayama, 54(6), 259-264.

Rat small intestinal transplantation : A comparison of the cuff and hand-suture methods. / Nakao, Atsunori; Mitsuoka, Naoshi; Shen, Sun Don; Tanaka, Noriaki; Kobayashi, Eiji.

In: Acta Medica Okayama, Vol. 54, No. 6, 2000, p. 259-264.

Research output: Contribution to journalArticle

Nakao, A, Mitsuoka, N, Shen, SD, Tanaka, N & Kobayashi, E 2000, 'Rat small intestinal transplantation: A comparison of the cuff and hand-suture methods', Acta Medica Okayama, vol. 54, no. 6, pp. 259-264.
Nakao, Atsunori ; Mitsuoka, Naoshi ; Shen, Sun Don ; Tanaka, Noriaki ; Kobayashi, Eiji. / Rat small intestinal transplantation : A comparison of the cuff and hand-suture methods. In: Acta Medica Okayama. 2000 ; Vol. 54, No. 6. pp. 259-264.
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