Rapid oscillatory activity in delta brushes of premature and term neonatal EEG

Derrick W.S. Chan, Madoka Yamazaki, Tomoyuki Akiyama, Bill Chu, Elizabeth J. Donner, Hiroshi Otsubo

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We compared frequency and power of neonatal EEG delta brush rapid oscillatory activity (ROA) using multiple band frequency analysis (MBFA) in three groups; pre-term (PT, post-conceptional age 33-35.6weeks, n=5); full-term (FT, 39.4-40.6weeks, n=5) and pre-term or full-term with phenobarbital exposure (PB, n=5). Mean number of delta brushes analyzed was 29.4 (range 26-47) in PT, 20.8 (14-33) in FT and 20 (7-37) in PB. Mean frequency±standard deviation (s.d.) was 16.9±2.1Hz (range 15-20Hz) in PT, 17.3±1.9Hz (15-20Hz) in FT and 16.1±1.6Hz (14-19Hz) in PB. Mean power±s.d. was 22.9±6.2μV2 (range 16-39μV2) in PT, 11.9±4.1μV2 (7-19μV2) in FT and 17.1±6.2μV2 (9-26μV2) in PB. Power was significantly higher in PT than FT (p<0.005). Power after merging PB into respective PT (PT′, n=8) and FT (FT′, n=7) groups, remained significantly higher in PT′ (mean±s.d. 21.8±7.4μV2) than FT′ (11.4±3.6μV2) (p<0.05). We characterise ROA in delta brushes in maturing neonates using MBFA, which may provide additional information for assessing future seizure recurrence and epilepsy risk.

Original languageEnglish
Pages (from-to)482-486
Number of pages5
JournalBrain and Development
Volume32
Issue number6
DOIs
Publication statusPublished - Jun 1 2010
Externally publishedYes

Keywords

  • Delta brush
  • Multiple band frequency analysis
  • Neonatal EEG
  • Rapid oscillatory activity

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Clinical Neurology

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