Abstract
A young woman with primary pulmonary hypertension developed severe interstitial pneumonia (IP) 5 days after induction of epoprostenol infusion. Although the pathogen involved was not identified, her IP was initially responsive to steroids, and discontinuation of steroid therapy caused the redevelopment of IP. After intensive treatment, including steroid therapy and inhaled nitric oxide, epoprostenol was successfully switched to prostaglandin E1 infusion and she recovered. Epoprostenol infusion can cause a rapid severe IP, even soon after the induction of therapy. Clinicians should keep this syndrome in mind, especially when treating a severe case of IP.
| Original language | English |
|---|---|
| Pages (from-to) | 1205-1207 |
| Number of pages | 3 |
| Journal | Anesthesia and Analgesia |
| Volume | 99 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Oct 2004 |
Fingerprint
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
Cite this
Rapid development of severe interstitial pneumonia caused by epoprostenol in a patient with primary pulmonary hypertension. / Morimatsu, Hiroshi; Goto, Keiji; Matsusaki, Takashi; Katayama, Hiroshi; Matsubara, Hiromi; Ohe, Tohru; Morita, Kiyoshi.
In: Anesthesia and Analgesia, Vol. 99, No. 4, 10.2004, p. 1205-1207.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Rapid development of severe interstitial pneumonia caused by epoprostenol in a patient with primary pulmonary hypertension
AU - Morimatsu, Hiroshi
AU - Goto, Keiji
AU - Matsusaki, Takashi
AU - Katayama, Hiroshi
AU - Matsubara, Hiromi
AU - Ohe, Tohru
AU - Morita, Kiyoshi
PY - 2004/10
Y1 - 2004/10
N2 - A young woman with primary pulmonary hypertension developed severe interstitial pneumonia (IP) 5 days after induction of epoprostenol infusion. Although the pathogen involved was not identified, her IP was initially responsive to steroids, and discontinuation of steroid therapy caused the redevelopment of IP. After intensive treatment, including steroid therapy and inhaled nitric oxide, epoprostenol was successfully switched to prostaglandin E1 infusion and she recovered. Epoprostenol infusion can cause a rapid severe IP, even soon after the induction of therapy. Clinicians should keep this syndrome in mind, especially when treating a severe case of IP.
AB - A young woman with primary pulmonary hypertension developed severe interstitial pneumonia (IP) 5 days after induction of epoprostenol infusion. Although the pathogen involved was not identified, her IP was initially responsive to steroids, and discontinuation of steroid therapy caused the redevelopment of IP. After intensive treatment, including steroid therapy and inhaled nitric oxide, epoprostenol was successfully switched to prostaglandin E1 infusion and she recovered. Epoprostenol infusion can cause a rapid severe IP, even soon after the induction of therapy. Clinicians should keep this syndrome in mind, especially when treating a severe case of IP.
UR - http://www.scopus.com/inward/record.url?scp=4644326862&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=4644326862&partnerID=8YFLogxK
U2 - 10.1213/01.ANE.0000130615.28893.52
DO - 10.1213/01.ANE.0000130615.28893.52
M3 - Article
C2 - 15385376
AN - SCOPUS:4644326862
VL - 99
SP - 1205
EP - 1207
JO - Anesthesia and Analgesia
JF - Anesthesia and Analgesia
SN - 0003-2999
IS - 4
ER -